Teen sexual behavior in the form of desire encourages adolescents to perform sexual behavior, both with the opposite sex or same sex. So there are still many teenage girls who drop out due to sexual behavior that deviates. The purpose of this study was to investigate factor analysis related to female teen sexual behavior in SMA N 10 Kota Bengkulu. This research uses an analytic survey method, a cross-sectional approach. The population used are girls of class X and IX SMA N 10 Kota Bengkulu. Samples were taken by stratified random sampling by lottery technique; the number of respondents was 124 students. The result of Chi-Square test is known that knowledge less heavy sexual behavior as much as (98,4%), whereas good knowledge of behavior of light sex as much (81,5%), unfavorable attitude on adolescent girls do heavy sexual behavior as much (80%), While favorable attitude of female teenagers who engage in light sexual behavior as much as (52,5%). Unfavorable parental parenting pattern toward adolescent girls do hard sex behavior as much as 53 (77,9%), while parenting pattern favorable in adolescent Daughter performed sexual behavior light as much as (51,8%). There was a significant correlation between knowledge and sexual behavior of adolescent girls p=0.000, attitude with female teen sex behavior p=0,000 OR=4,429 and pattern of parenting with female teen sex behavior p=0,001 OR=4,429. Multivariate analysis result obtained that the most dominant factor is knowledge p=0,000, OR=11,515. To the School is expected to conduct counseling, counseling to provide knowledge to adolescents about the dangers of sexual behavior and parents should further improve the supervision of their children.