Silentes CTG in der 32. Schwangerschaftswoche unter Midazolam oder peripartale Infektion?

Athanassiou, N.; Kufus, S.; Künzel, W.

doi:10.1007/s001290050498

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“…Allerdings muss bedacht werden, dass die Gabe von Benzodiazepinen unter Umständen auch zu einer Verschleierung pathologischer Herzfrequenzmuster führen kann und z. B. Dezelerationen, als Ausdruck einer fetalen O 2 -Mangelversorgung, nicht zu Tage treten[7].In der hier vorgestellten Fallstudie kann das abwartende Verhalten retrospektiv als richtige Entscheidung gewertet werden. Eine Intervention durch Schnittentbindung hätte mit an Sicherheit grenzender Wahrscheinlichkeit zur Entwicklung eines unreifen, deprimierten Kindes mit einer erheblichen respiratorischen Anpassungsstörung geführt.…”

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Silentes CTG - Hypoxie oder Intoxikation?

Stähle

Melchert²,

Weigel³

2003

Z Geburtshilfe Neonatol

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A fetal heart-rate pattern that has a reduced oscillation amplitude may indicate a physiological fetal dormant period but could also be an indication of fetal hypoxemia. In some rare cases such a fetal heart rate-pattern can be an indicator of cerebral or cardial fetal malformation or of an intoxication caused by sedative drugs. Our patient is a 32-year-old Para III in the phase of 29 weeks and 3 days gestation. Upon admission to the clinic, the fetal heart-rate pattern showed a reduced oscillation amplitude, and there were no signs of fetal movement. The ultrasound examination gave us no reason to suspect fetal malformation, and the results of the Doppler ultrasonography were also normal. However, although the patient had denied taking any medication at all, the results of an toxicological blood test confirmed our suspicion of benzodiazepine intoxication. Throughout the night the fetal heart-rate pattern was continuously measured, and in the early hours of the morning, after breaking down of the oxazepam medication, a normalization of the fetal heart-rate pattern was observed. This case report definitively demonstrates that Doppler ultrasonography is a valuable method for assessing any uncertainty regarding a fetal heart-rate pattern.

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