Silicon effect on the composition and structure of nanocalcium phosphates

Tomoaia, Gheorghe; Mocanu, Aurora; Vida–Simiti, Ioan; Jumate, Nicolaie; Bobos, Liviu-Dorel; Şoriţău, Olga; Tomoaia-Cotişel, Maria

doi:10.1016/j.msec.2013.12.027

Cited by 55 publications

(50 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…4a was obtained from the b-TCP coating surface, which shows rounded particles overlapped between them, taking into account that the scale of measurements is a clear evidence that this coating is obtained from nanopowder. In addition, a qualitative analysis indicates that the sample contains predominantly particles of almost the same size and shape similar to the results reported by previous publications [32,33]. The allotropic changes in the surface morphology of the b-TCP þ Ch coatings were described previously, indicating that these changes are related to the changing in the size and distribution of the particles.…”

Section: Surface Coating Analysissupporting

confidence: 87%

Determination of physical properties for β-TCP + chitosan biomaterial obtained on metallic 316L substrates

Mina

Castano

Caicedo

et al. 2015

Materials Chemistry and Physics

View full text Add to dashboard Cite

Section: Surface Coating Analysissupporting

confidence: 87%

Determination of physical properties for β-TCP + chitosan biomaterial obtained on metallic 316L substrates

Mina

Castano

Caicedo

et al. 2015

Materials Chemistry and Physics

View full text Add to dashboard Cite

“…Synthesis, structural and mechanical studies, and in vitro analysis of CaPs with ionic incorporation have been reported, namely Mg, Sr, Zn, Na, F,, Ag, Mn, Si, and Ba . Kose et al showed that silver ion‐containing CaP‐based ceramic nanopowder‐coated implants led to an increase in resistance to bacterial colonization compared to HAp‐coated, and uncoated titanium implants.…”

Section: Calcium Phosphate‐based Materialsmentioning

confidence: 99%

“…In vitro proliferation and differentiation assays of MC3T3‐E1 osteoblastic‐like cells, grown in the presence of the powders, revealed that the biological benefits of Mn‐doped β‐TCP are limited to lower Mn incorporation levels and potentially related to their surface microstructure. Another interesting work prepared Si‐substituted nano‐CaPs followed by the fabrication of multilayered scaffolds . In that study, it was reported that the silicon content facilitates a progressive change of nano‐HAp structure to nano‐TCP, and enhanced adhesion, spreading, growth and proliferation of osteoblasts on the scaffolds, which might be considered for bone tissue engineering, with potential applications in bone reconstruction and regeneration.…”

Section: Calcium Phosphate‐based Materialsmentioning

confidence: 99%

Natural‐Based Nanocomposites for Bone Tissue Engineering and Regenerative Medicine: A Review

2015

View full text Add to dashboard Cite

Tissue engineering and regenerative medicine has been providing exciting technologies for the development of functional substitutes aimed to repair and regenerate damaged tissues and organs. Inspired by the hierarchical nature of bone, nanostructured biomaterials are gaining a singular attention for tissue engineering, owing their ability to promote cell adhesion and proliferation, and hence new bone growth, compared with conventional microsized materials. Of particular interest are nanocomposites involving biopolymeric matrices and bioactive nanosized fillers. Biodegradability, high mechanical strength, and osteointegration and formation of ligamentous tissue are properties required for such materials. Biopolymers are advantageous due to their similarities with extracellular matrices, specific degradation rates, and good biological performance. By its turn, calcium phosphates possess favorable osteoconductivity, resorbability, and biocompatibility. Herein, an overview on the available natural polymer/calcium phosphate nanocomposite materials, their design, and properties is presented. Scaffolds, hydrogels, and fibers as biomimetic strategies for tissue engineering, and processing methodologies are described. The specific biological properties of the nanocomposites, as well as their interaction with cells, including the use of bioactive molecules, are highlighted. Nanocomposites in vivo studies using animal models are also reviewed and discussed.

show abstract

“…Forsterite ceramic, FC-1200, was subjected to cells viability test to determine its biocompatibility in vitro [5,[34][35][36][37][38][39]. The MTT assay is preferred over the other methods of measuring cells viability as it is a sensitive and reliable indicator of the cellular metabolic activity [35,37,38].…”

Section: Cell Viabilitymentioning

confidence: 99%

Novel Porous Forsterite Ceramics Biocompatibility and Bioactivity Evaluation

Gorea¹,

Naghiu²,

Avram³

et al. 2020

Rev. Chim.

Self Cite

View full text Add to dashboard Cite

This study is aimed to evaluate the biocompatibility and bioactivity of some new porous forsterite ceramics (FCs) produced from high-purity nano forsterite powder, synthesized by an original sol-gel method, which was subjected to pressing into pellets, by using a poly vinyl alcohol solution as a binding component. Then, the raw pellets were sintered at 1200 �C, 1300 �C, 1400 �C and 1450 �C. The obtained four forsterite ceramics, FC-1200, FC-1300, FC-1400 and FC-1450, were fully characterized by density, porosity and shrinkage measurements. The forsterite ceramics exhibited excellent biocompatibility determined by an in vitro cell viability assay, such as MTT test. Furthermore, the in vitro bioactivity test was performed by immersing the forsterite ceramics into simulated body fluid (SBF) and examining the hydroxyapatite (HAP) formation on forsterite ceramics, as evidenced by XRD, FTIR, SEM with EDX. Moreover, the relationship between porous structure and bioactivity of forsterite ceramics in SBF as well as the performance of FC in a cell culture was evaluated. The findings strongly recommend these forsterite ceramics for biomedical applications, as potential bone substitutes.

show abstract

Silicon effect on the composition and structure of nanocalcium phosphates

Cited by 55 publications

References 40 publications

Determination of physical properties for β-TCP + chitosan biomaterial obtained on metallic 316L substrates

Determination of physical properties for β-TCP + chitosan biomaterial obtained on metallic 316L substrates

Natural‐Based Nanocomposites for Bone Tissue Engineering and Regenerative Medicine: A Review

Novel Porous Forsterite Ceramics Biocompatibility and Bioactivity Evaluation

Contact Info

Product

Resources

About