Silicone Oil Implantation in Penetrating Injuries Complicated by PVR

Skorpik, Christian; Menapace, Rupert; Gnad, H. D.; Paroussis, P

doi:10.1097/00006982-198909010-00002

Cited by 24 publications

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“…2005;123:473-478 S ILICONE OIL WAS FIRST REported for the treatment of retinal detachment in 1962 1 and has been used increasingly as a retinal tamponade in the management of complex retinal detachments associated with cytomegalovirus necrotizing retinitis, [2][3][4][5][6][7][8][9][10][11] proliferative diabetic retinopathy, [12][13][14][15][16][17][18] giant retinal tears, [19][20][21][22][23][24][25][26][27][28] proliferative vitreoretinopathy, [29][30][31][32][33][34][35][36][37] and ocular trauma. [38][39][40][41][42][43][44][45] The National Eye Institute Silicone Study demonstrated the superiority of 1000-centistoke silicone oil compared with sulfur hexafluoride, and its comparability with perfluoropropane, for the treatment of complex retinal detachment associated with advanced p...…”

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confidence: 99%

Outcomes of Complex Retinal Detachment Repair Using 1000- vs 5000-Centistoke Silicone Oil

et al. 2005

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To compare anatomic and visual acuity outcomes, as well as complication rates, after retinal detachment repair using 1000-vs 5000-centistoke silicone oil. Methods: Records of all patients who underwent retinal detachment repair with silicone oil at one institution between January 1, 1995, and December 31, 2000, were reviewed. Anatomic outcomes included retinal redetachment and macula-off retinal redetachment. Visual acuity outcomes included ambulatory vision (Ն5/200) and change in visual acuity from preoperative examination. Complications included rates of secondary intraocular pressure elevation, hypotony, corneal opacification, cataract, and oil emulsification. Outcomes were assessed at 1 week, 1 month, 3 months, 6 months, and 1 year. Results: The study included 82 eyes that underwent retinal detachment repair with 1000-centistoke silicone oil and 243 eyes that underwent retinal detachment repair with 5000-centistoke silicone oil. Demographic characteristics, cause of retinal detachment, and preoperative

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confidence: 99%

Outcomes of Complex Retinal Detachment Repair Using 1000- vs 5000-Centistoke Silicone Oil

et al. 2005

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“…An overall reattachment rate of 78.18% and functional success of 56.36% has been reported, while those that had proliferative vitreoretinopathy and underwent silicone oil implantation had a reattachment rate of 63.64% 29. Other investigators reported total reattachment caused by trauma in silicone oil-filled eyes in 52%–62% of cases 30. In the current study, silicone oil 5000 was used in all cases to prevent rebleeding from the exit wound.…”

Section: Discussionmentioning

confidence: 71%

Vitrectomy in double-perforation gunshot injury

Mohamed

2013

OPTH

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ObjectiveThis study sought to evaluate the result of pars plana vitrectomy in patients with gunshot wounds involving double perforation.MethodsThis was a retrospective, noncomparative, interventional case series.ResultsEighteen patients (18 eyes) with double-perforation gunshot injuries were treated from February 2010 to March 2012. The group included 16 men (88%) and two women (11%); the mean age was 24 (15–33) years. In each case, vitrectomy was scheduled 1–6 weeks after repair of the entrance site. Associated retinal detachments were observed in two eyes (11%), retinal incarceration was observed surrounding the exit site in three eyes (16%), and retention of an intraocular foreign body was observed in two cases. After a follow-up period of 8 ± 2 months, two eyes (11%) had achieved visual acuity (VA) of 0.5, nine eyes (50%) had achieved VA between 0.5 and 0.1, and seven eyes (38%) had achieved VA between 0.1 and hand movement. The main reasons for functional failure (VA 0.1 to hand movement) were macular dragging (due to fibrosis at the exit site near the macula) in seven cases (38%), submacular hemorrhage in four cases (22%), and epimacular fibrosis in five cases (27%). All cases developed postoperative exotropia. One case (5%) developed postoperative hemorrhage. No cases exhibited signs of postoperative redetachment.ConclusionThe outcome of pars plana vitrectomy in cases with double perforations is variable. Factors including the surgeon’s skill level, the time to surgery, and the efficacy of the intraocular tamponade affect the postoperative outcome.

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“…Related silicone materials find increasing use in medical applications as bioengineered fluids, implant materials, and drug delivery vehicles. Silicone oil (SO), which is often composed of linear PDMS, has been employed as a temporary vitreous substitute in retinal detachment . However, it was discovered recently that contact with silicone materials inhibited human corneal endothelial cell and mouse mammary fibroblast proliferation, , thus raising concerns about biocompatibility.…”

Section: Introductionmentioning

confidence: 99%

Measuring Interactions between Polydimethylsiloxane and Serum Proteins at the Air–Water Interface

et al. 2013

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The interaction between synthetic polymers and proteins at interfaces is relevant to basic science as well as a wide range of applications in biotechnology and medicine. One particularly common and important interface is the air-water interface (AWI). Due to the special energetics and dynamics of molecules at the AWI, the interplay between synthetic polymer and protein can be very different from that in bulk solution. In this paper, we applied the Langmuir-Blodgett technique and fluorescence microscopy to investigate how the compression state of polydimethylsiloxane (PDMS) film at the AWI affects the subsequent adsorption of serum protein [e.g., human serum albumin (HSA) or immunoglobulin G (IgG)] and the interaction between PDMS and protein. Of particular note is our observation of circular PDMS domains with micrometer diameters that form at the AWI in the highly compressed state of the surface film: proteins were shown to adsorb preferentially to the surface of these circular PDMS domains, accompanied by a greater than 4-fold increase in protein found in the interfacial film. The PDMS-only film and the PDMS-IgG composite film were transferred to cover glass, and platinum-carbon replicas of the transferred films were further characterized by scanning electron microscopy and atomic force microscopy. We conclude that the structure of the PDMS film greatly affects the amount and distribution of protein at the interface.

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Silicone Oil Implantation in Penetrating Injuries Complicated by PVR

Cited by 24 publications

References 0 publications

Outcomes of Complex Retinal Detachment Repair Using 1000- vs 5000-Centistoke Silicone Oil

Outcomes of Complex Retinal Detachment Repair Using 1000- vs 5000-Centistoke Silicone Oil

Vitrectomy in double-perforation gunshot injury

Measuring Interactions between Polydimethylsiloxane and Serum Proteins at the Air–Water Interface

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