Silk Nanofibrous Electrospun Scaffold Amplifies Proliferation and Stemness Profile of Mouse Spermatogonial Stem Cells

Improving motor neuron-like cell differentiation of hEnSCs by the combination of epothilone B loaded PCL microspheres in optimized 3D collagen hydrogel

“…Cell attachment to the ECM is crucial for cell differentiation and proliferation via cell anchoring and activation of signaling pathways that can lead to tissue regeneration and development 69 – 71 . Collagen is a key component of the ECM and is extensively used as a scaffold for its effective properties of improving cell attachment, survival, proliferation, differentiation, and migration 72 .…”

Bridging potential of Taurine-loading PCL conduits transplanted with hEnSCs on resected sciatic nerves

“…Within the last decades, fabricating methods could improve the structure of nerves in terms of appropriate permeable and biodegradable porous conduits, along with ideal tensile strength in resisting in vivo mechanical forces [ 16 ]. Electrospinning is an eminent technique to produce nanofibers with suitable porosity, degradability, mechanical properties, and extensive surface to volume for compatible cell attachment [ 17 , 18 ]. These special characteristics of nanofibers structures persuade wide investigation on its application for neural tissue engineering [ [12] , [13] , [14] , [15] , [19] , [20] , [21] ].…”