Silk scaffolds for dental tissue engineering

Jindal, Swati; Kiamehr, Mostafa; Sun, Weibin; Yang, Xuebin

doi:10.1533/9780857097064.3.403

Cited by 8 publications

(2 citation statements)

References 132 publications

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“…Silk-based biomaterial scaffolds have been extensively used for both soft and hard tissue engineering. [ 50 ]…”

Section: Scaffoldsmentioning

confidence: 99%

“…Silk fibroin (SF) is an enzymatically degradable material, which can be processed into water insoluble implants, injectable hydro gels, and porous sponges. [ 50 ] The ability of SF to support vascularization with good anticoagulant activity and platelet response is encouraging for tissue engineering research and clinical therapy in dentistry. [ 51 ] It has good mechanical strength, elasticity, biodegradability, morphologic flexibility, oxygen and water permeability, and a slow degradation rate that enables gradual replacement of fibroin with newly formed tissue.…”

Section: Scaffoldsmentioning

confidence: 99%

See 1 more Smart Citation

Scaffolds in regenerative endodontics: A review

Gathani

Raghavendra

2016

Dent Res J

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Root canal therapy has enabled us to save numerous teeth over the years. The most desired outcome of endodontic treatment would be when diseased or nonvital pulp is replaced with healthy pulp tissue that would revitalize the teeth through regenerative endodontics. ‘A search was conducted using the Pubmed and MEDLINE databases for articles with the criteria ‘Platelet rich plasma’, ‘Platelet rich fibrin’, ‘Stem cells’, ‘Natural and artificial scaffolds’ from 1982–2015’. Tissues are organized as three-dimensional structures, and appropriate scaffolding is necessary to provide a spatially correct position of cell location and regulate differentiation, proliferation, or metabolism of the stem cells. Extracellular matrix molecules control the differentiation of stem cells, and an appropriate scaffold might selectively bind and localize cells, contain growth factors, and undergo biodegradation over time. Different scaffolds facilitate the regeneration of different tissues. To ensure a successful regenerative procedure, it is essential to have a thorough and precise knowledge about the suitable scaffold for the required tissue. This article gives a review on the different scaffolds providing an insight into the new developmental approaches on the horizon.

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“…Silk-based biomaterial scaffolds have been extensively used for both soft and hard tissue engineering. [ 50 ]…”

Section: Scaffoldsmentioning

confidence: 99%

Section: Scaffoldsmentioning

confidence: 99%