Silver nanoparticles synthesis using AH leaf extract and its antimicrobial activity

Abstract

Crystallized silver nanoparticles (AgNPs) were synthesized by using the eco-friendly Artocarpus heterophyllus biomaterial. The synthesis of AgNPs was a green approach and a rapid method. The AgNPs were characterized by field-emission scanning electron microscopy (FE-SEM), Fourier transform infrared spectroscopy, X-ray diffraction and inductively coupled plasma atomic emission spectroscopy. The FE-SEM analysis showed that the size of the synthesized AgNPs ranged around 45 nm. The plant leaves acted as both a reducing and a capping agent. The synthesized AgNPs showed an absorption peak at 400–440 nm. The biosynthesized AgNPs were tested for their antimicrobial activity against both the gram-positive bacterium Staphylococcus aureus and the gram-negative bacterium Escherichia coli and the fungus Aspergillus niger. The method used in the present work is simple, rapid, single-step, environment-friendly and very cheap and is an alternative to the current physicochemical methods. The antimicrobial activity of biosynthesized AgNPs suggests their possible application in the medical and pharmaceutical industry.

Natural product‐based nanomedicine applied to fungal infection treatment: A review of the last 4 years

“…To guarantee that the nanoparticles are formed and to evaluate their characteristics, it is fundamental to carry out characterization analyses. The following characterization analyses are widely used: surface plasmon resonance (SPR), to confirm the nanoparticle formation; UV–Vis Spectrophotometer, for monitoring metal ions reduction; FT‐IR, for functional group analysis; scanning electron microscope (SEM) and high‐resolution transmission electron microscope (HR‐TEM) analyses, for determination of size and shape; X‐ray diffractometer analyses, to evaluate its purity and crystalline structure; and thermogravimetric analysis, to monitor weight loss percentage and thermal stability (Botteon et al, 2021; Manjare et al, 2020; Moustafa, 2021; Qayyum et al, 2020; Shanmugapriya et al, 2021; Ulaeto et al, 2020).…”

“…AgNPs were biosynthesized in another study, using Artocarpus heterophyllus leaf extract, and tested in vitro against some pathogens such as A . niger (Manjare et al, 2020). It is worth mentioning that this plant has antifungal activity and, therefore, its use as a reducing and capping agent is desirable (Manjare et al, 2020; Vázquez‐González, Ragazzo‐Sánchez, & Calderón‐Santoyo, 2020).…”

“…and high-resolution transmission electron microscope (HR-TEM) analyses, for determination of size and shape; X-ray diffractometer analyses, to evaluate its purity and crystalline structure; and thermogravimetric analysis, to monitor weight loss percentage and thermal stability (Botteon et al, 2021;Manjare et al, 2020;Moustafa, 2021;Qayyum et al, 2020;Shanmugapriya et al, 2021;Ulaeto et al, 2020).…”

“…AgNPs were biosynthesized in another study, using Artocarpus heterophyllus leaf extract, and tested in vitro against some pathogens such as A. niger (Manjare et al, 2020). It is worth mentioning that this plant has antifungal activity and, therefore, its use as a reducing and capping agent is desirable (Manjare et al, 2020;Vázquez-González, Ragazzo-Sánchez, & Calder on-Santoyo, 2020). Although the nanoparticles showed a smaller inhibition zone than the control (penicillin) in the agar-well diffusion method, 0.9 and 2.3 mm, respectively, the authors believe that the AgNP showed significant antifungal activity.…”

Synthesis of Plant-Mediated Silver Nanoparticles Using Cyperus Difformis Flower Extract and Evaluation of Its Antioxidant and Anticancerous Activity

“…Generally, metal nanoparticles are produced by using either the physiochemical , (Abbas et al, 2019), (Sreedhar, Surendra Reddy, and Keerthi Devi 2009) or green method (Shah et al, 2021), (Gnanadesigan et al, 2011), (Singhal et al, 2011). The biosynthesis of AgNPs using extract of leaves of Artocarpus heterophyllus (Manjare, Paranjape, et al, 2020) and Carissa carandas (Manjare, Sharma, et al, 2020) has been reported.…”