Simple anonychia. Further evidence for autosomal recessive inheritance.

Simple congenital anonychia in an Iranian family

“…In literature review there were rare case reports of total or near total simple anonychia with AR inheritance pattern especially in Iran, Saudi Arabia, Turkey, India and Kazakhstan probably due to consanguineous marriages [1][2][3][4]6,[8][9][10][11]. We reported this case because of rare presentation but we guess it is not an extremely rare disorder and probably some of these cases have been unreported as it has been shown in our patient pedigree.…”

Autosomal Recessive Total Congenital Anonychia, in a Saudi family

“…This rare genetic disorder has been reported in individuals from different countries around the world. Previous report [1], had indicated that it could be found in countries such as, Russia, Great Britain, America, Holland, Iran. Recently, it has been reported in Brazil [2] and Turkey [3].…”

Congenital complete simple anonychia

“…Most of the reported congenital cases have been incomplete, there may be some rudimentary nails in one or more fingers or toes [1,6]. Congenital complete anonychia (congenital absence of nails on all fingers and toes) is a much rarer form of this anomaly [7]. Anonychia may result when the underlying bone is either hypoplastic or completely absent [2].…”

“…In a literature review, simple anonychia is observed to mostly show an inheritance pattern, either autosomal recessive or as a new mutation [4,6,7]. A newborn with simple, complete congenital anonychia lacking an inheritance pattern of any kind is presented.…”

“…Simple anonychia (congenital absence of nails without any defects in other structures) is an extremely rare aspect of congenital complete anonychia [6,7]. In a literature review, simple anonychia is observed to mostly show an inheritance pattern, either autosomal recessive or as a new mutation [4,6,7].…”