Simple dipstick assay for semi-quantitative detection of neopterin in sera

Sorologia PGL-I na hanseníase

“…The techniques used to develop tests include the enzyme-linked immunosorbent assay (ELISA) 3 , the passive hemagglutination test (PHA) 15 , a gelatin particle agglutination test (MLPA) 13 , the dipstick 5 and the lateral flow test 6 . An expressive part of the studies published so far have used the ELISA, dipstick and lateral flow techniques.…”

Serum neopterin levels in patients with brucellosis

“…1,2 A follow-up of serum NPT concentrations during the course of an infectious disease could be useful for measuring the activity of the disease and the efficiency of treatment. [3][4][5][6][7] In this study, we aimed to detect NPT levels in patients with brucellosis, its role in prognostic value for follow-up and particularly its usage in early determination of those not responding to the treatment.…”

Seroreactivity to new Mycobacterium leprae protein antigens in different leprosy-endemic regions in Brazil

“…Anti-PGL-I positivity reflects the bacillary load: most MB patients are seropositive, while the majority of PB patients are seronegative (Young & Buchanan 1983. Although anti-PGL-I serology has limited application for the diagnosis of all clinical forms of leprosy, it has been suggested as an important adjunct tool for the differentiation of PB and MB leprosy (Bührer-Sékula et al 2000. More recently, in the post-genomic era, data regarding seroreactivity to novel M. leprae protein antigens have been generated in various populations worldwide.…”