Simple Sonochemical Method to Optimize the Heating Efficiency of Magnetic Nanoparticles for Magnetic Fluid Hyperthermia

Abstract

We developed a fast, single-step sonochemical strategy for the green manufacturing of magnetite (Fe 3 O 4 ) magnetic nanoparticles (MNPs), using iron sulfate (FeSO 4 ) as the sole source of iron and sodium hydroxide (Na(OH)) as the reducing agent in an aqueous medium. The designed methodology reduces the environmental impact of toxic chemical compounds and minimizes the infrastructure requirements and reaction times down to minutes. The Na(OH) concentration has been varied to optimize the final size and magnetic properties of the MNPs and to minimize the amount of corrosive byproducts of the reaction. The change in the starting FeSO 4 concentration (from 5.4 to 43.1 mM) changed the particle sizes from (20 ± 3) to (58 ± 8) nm. These magnetite MNPs are promising for biomedical applications due to their negative surface charge, good heating properties (≈324 ± 2 W/g), and low cytotoxic effects. These results indicate the potential of this controlled, easy, and rapid ultrasonic irradiation method to prepare nanomaterials with enhanced properties and good potential for use as magnetic hyperthermia agents.

Innovative nanostructured magnetite/wool/polysiloxane composite as magnetic adsorbent for oil spill removal

“…The magnetic characterization reveals that the studied sample exhibit a standard ferromagnetic character [33]. Likewise, the saturation magnetization M S value of 70.64 emu•g −1 and the coercivity value of 2.31 Oe are in close agreement with previous reports on magnetite [33,34]. In addition, the morphology of the synthesized Fe 3 O 4 nanoparticles was investigated by using the transmission electron microscopy (TEM).…”

Magnetite Nanoparticles: Synthesis and Applications in Optics and Nanophotonics

“…Nevertheless, the authors concluded that the magnetic characteristics of the nanoparticles obtained were lower than that of nanoparticles produced without ultrasound assistance due to the size difference. Fuentes-García and co-authors [ 69 ] developed a fast, single-step sonochemical strategy for the green manufacturing of magnetite nanoparticles, using iron sulfate as the sole source of iron and sodium hydroxide as the reducing agent in an aqueous medium. They reported that the sodium hydroxide concentration was varied to optimize the final size and magnetic properties of the magnetite nanoparticles and to minimize the number of corrosive byproducts from the reaction.…”

Iron Oxide Nanoparticles and Nano-Composites: An Efficient Tool for Cancer Theranostics

“…The particle can be transformed into a highly crystalline form by subjecting them to higher temperature, following the sonochemical synthesis [53]. A cube-like Fe 3 O 4 nanoparticle with different particle sizes ranging from 20 to 58 nm was obtained by varying the molar concentration of the precursor and the reducing agent [54]. According to the LaMer model, the local supersaturation should be higher to achieve the smaller particles.…”