Simulation based investigation of 2D soft-elastic reactors for better mixing performance

Li, Changyong; Gasow, Stefan; Jin, Yan; Xiao, Jie; Chen, Xiao

doi:10.1080/19942060.2021.1955746

Cited by 3 publications

(2 citation statements)

References 36 publications

(35 reference statements)

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“…The intestine refers to the digestive tube from the pylorus of the stomach to the anus, and is the longest section of the digestive tube, as well as the most important section in terms of function. The mammalian intestine contains three major segments: large intestine, small intestine and rectum [1]. A large amount of digestion and absorption of almost all digestive products are carried out in the small intestine; the large intestine mainly concentrates food residues and forms feces, which is excreted through the rectum via the anus [2].…”

Section: Introductionmentioning

confidence: 99%

Simulation Analysis of Small Intestinal Peristalsis Based on Finite Element

Liu¹

2023

AETR

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Based on COMSOL Multiphysics, a two-dimensional model of the duodenum of the small intestine was established and simulated to obtain the flow rate of the duodenum under different chyme viscosity and different boundary loads. The results show that: when other conditions remain the same, the outlet flow rate decreases with the increase of the chyme viscosity with significant differences; the outlet flow rate increases with the increase of the boundary loads, and the flow rate only changes significantly when the boundary load is greater than 1.0×10-5 N/mm2.

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Section: Introductionmentioning

confidence: 99%

Simulation Analysis of Small Intestinal Peristalsis Based on Finite Element

Liu¹

2023

AETR

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“…CFD can simulate the motility and geometry of the intestinal system. The flow patterns in the digestion process have been examined by some developed CFD models to study fundamental mechanisms, including 2D (two-dimensional) CFD [7][8][9] and 3D (three-dimensional) CFD [10][11][12][13] models. The behavior of Newtonian fluids has been studied by Ferrua and Singh [13] for gastric flow by a CFD simulation, allowing the prediction and visualization of the flow patterns, shear stresses, and shear rates.…”

Section: Introductionmentioning

confidence: 99%

Simulating Flow in an Intestinal Peristaltic System: Combining In Vitro and In Silico Approaches

Liu,

Zhong,

Fletcher

et al. 2023

Fluids

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Transport and mixing in the gastric duct occur via peristaltic flow. In vivo data are hard to collect and require strict ethical approval. In contrast, both in vitro and in silico studies allow detailed investigation and can be constructed to answer specific questions. Therefore, the aim of this study was to design a new elastic thermoplastic polyurethane (TPU) intestine model and to compare the flow patterns observed experimentally with those predicted by a Fluid Structure Interaction (FSI) simulation. Here, we present complementary studies that allow feedback to improve both techniques and provide mutual validation. The experimental work provides direct measurement of mixing, and the simulation allows the experimental setup to be studied to determine the impacts of various parameters. We conclude by highlighting the utility of this approach.

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