The process parameters were optimized by simulation and verification experiments using orthogonal experimental design and the Taguchi method to lessen the tendency of significant shrinkage porosity in the centrifugal cast ring parts of K417 nickel-based superalloy. Advanced Porosity Model (APM) in ProCAST was used to predict the shrinkage porosity of centrifugal castings, and the effects of centrifugal speed, pouring speed, pouring temperature and preheating temperature of the mold were investigated on the shrinkage porosity ratio of the castings. According to the results, the parameter that has the greatest influence on the shrinkage porosity ratio of centrifugal casting is the centrifuge speed, followed by the preheating temperature of the mold, and the pouring temperature and pouring speed have relatively small effects on it. The optimized parameters were proposed as follows: centrifugal speed of 500 r/min, pouring speed of 225 mm/s, pouring temperature of 1400[Formula: see text], and mold preheating temperature of 50[Formula: see text], which could effectively reduce the formation of shrinkage porosity of the K417 centrifugal casting rings.