Broadband over Power Lines (BPL) is considered a promising communication technology in the concept of Smart Grids. This paper evaluates networks based on BPL, with a focus on the impact of repeaters in the linear topology of distribution substations. In large-scale Smart Grids network planning, positions of repeaters have to be carefully chosen. This article should help to determine such positions and limitations of BPL linear topology networks. Laboratory and on-field measurements and their results are presented in this article. Results show the impact of repeater’s deployment for different testing methodologies also with regard to other already presented studies. Measured values and the determined impacts of repeaters are later used as input data for simulation of the linear BPL topology in terms of network throughput with multiple streams and bottlenecks. These occur especially on lines shared by multiple communicating nodes. Furthermore, the simulation investigates the balancing time of multiple data streams throughput. The simulation shows that the throughput balancing can occupy a significant time slot, up to tens of seconds before the throughput of different streams balances. Also, the more data is generated, the more time the balancing time takes. Additionally, the throughput drop caused by a repeater is determined into the range of 35–60%. Based on the measurement and simulation results, lessons learned are presented, and possible performance improvements are discussed.