A 1050-O aluminum plate and a low carbon steel (SPCC) plate were seam welded by magnetic pulse welding (MPW). Experimental and numerical analysis methods were combined to investigate the wavy interface formation and local melting phenomena at the Al/Fe joint interface. The metallographic observation results showed that Al/Fe joint interface presents a trigger-like wave shape with two types of intermediate layers intermittently formed at the interface. Collision angle between two plates and impact velocity of Al sheet driven by electromagnetic force was numerically solved by coupled mechanical and electromagnetic fields analysis. The metal jet emission behavior, wavy interface formation process and the temperature change during MPW collision process was analyzed by SPH method. The numerical results showed that the temperature near the interface exceeds the melting point of both Al and Fe at extremely high pressure, which leads to the formation of a local melting zone (LMZ) where Al and Fe were mixed in melted state. The numerically reproduced wavy interface morphology showed a good consistency with the experimentally observed results.