The occurrence condition of coal seam differs greatly among various regions in China. The uneven development of coal mine safety production level in the North and South China is prominent. Due to the influence of personnel, equipment, mining technology, and other factors, the mortality rate per million tons of coal mines in A province in South China is 27 times the national average level. At present, not only the common factors such as enterprise safety production and government supervision, but also the pressure of regulatory and accountability, the pressure of social stability maintenance, and the external factors such as drastic changes in coal prices, coal supply guarantee, carbon peak and carbon neutralization, have imposed a double impact on coal mining enterprises and government supervision. The situation of coal mine safety production across China is very complex. In order to scientifically figure out the safety risk situation of coal mining enterprises in special periods and special areas, this study takes government supervisors, enterprise managers, underground front-line workers, and external factors as subjects and constructs a multi-dimensional safety risk evaluation system for coal mines in terms of work quality, work pressure, and economic factors. By horizontally and longitudinally comparing the scores of different main index factors, this system can timely discover the problems and weaknesses of supervisors at different levels and managers and front-line workers of different coal mining enterprises in the same region in work quality, work pressure, and economy, which can provide specific targeted suggestions for enterprises and governments on the safety management and safety supervision. This study not only pays attention to the hidden danger screening, risk control, and other factors that can directly reduce enterprise safety risks, but also considers the impact of personnel pressure, economic factors, external environment, and policy changes on the performance of safety production responsibilities by enterprise managers, government supervisors, and enterprise front-line workers. This is an innovation of this study. Finally, based on various subjective and objective weight calculation methods, a new comprehensive weight formula is proposed.