Due to its sustainable cooling design and inexpensive operation, desiccant based dehumidification and cooling systems have been popular in recent years for humid areas. In general, the desiccant cooling used in conjunction with evaporative cooling as two separate types of configurations according to direct or indirect cooling. The relative humidity of moist outside air can potentially be controlled by both the systems during dehumidification and cooling to produce indoor thermal comfort. The solid desiccant-assisted evaporative cooling technologies may enable the use of the technique in a wider variety of climates, including those with high humidity. The development of innovative desiccant materials, improvement of the structure and material of the dehumidifier setup, desorption consumption rate and operating strategy of the system are some of the potential research possibilities and recommendations that were made. According to this review study, the desiccant integrated innovative cooling system is found as promising alternative to the traditional vapor-compressed cooling system and with the right setup, may be used in hot, humid situations. Keywords: Dehumidification, Desiccant cooling, Performance, Regeneration.