Simultaneous Bilateral Renal Cell Carcinoma: Case Report and Review of the Literature

Metachronous bilateral renal cell carcinoma with an interval of more than 10 years

“…Some cases are metastatic from the contralateral RCC, while other cases are of a new and independent origin [2,3,15]. However, it is often difficult to differentiate these cases clinically, because these issues have not been well documented in the literature.…”

“…However, it is often difficult to differentiate these cases clinically, because these issues have not been well documented in the literature. In early studies some histopathological data were included as to whether such tumors were metastatic or represented bilateral primary disease [2,3].…”

“…In addition, in cases with a long interval, while it is supposed that metastasis may be less likely, in contrast, a de novo lesion may become more likely [2,3].…”

Aggressive surgical management of bilateral adenocarcinoma of the kidney

“…10 Small et al reviewed the English literature and reported the 18th case of documented simultaneous bilateral renal cell carcinoma in 1968, and the second case in which the condition was suspected preoperatively. 12 Flocks et al reported the third case of preoperatively diagnosed bilateral adenocarcinoma of the kidney, in January 1971; however, both kidneys were not operated on simultaneously.7 T h e case presented was diagnosed preoperatively and is the first in which simultaneous bilateral renal surgery was performed.…”