Simultaneous determination of ascorbic acid, dopamine and uric acid based on tryptophan functionalized graphene

Lian, Qianwen; He, Zhu; Qian, He; Luo, Ai Qin; Yan, Kaiwang; Zhang, Dongxia; Lu, Xiaoquan; Zhou, Xibin

doi:10.1016/j.aca.2014.03.032

Cited by 176 publications

(63 citation statements)

References 33 publications

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“…21 Lian et al have also reported a method for the detection of DA, AA and UA using graphene/tryptophan modified electrode from 0.5 to 110 μM. 9 Similarly, other DA sensors were reported using graphene, 9 carbon nanofiber, 22 carbon nanotube 23 and nitrogen doped carbon quantum dot (CQD). 24 CQD has the fluorescence behavior and has been utilized in various research fields such as photo-catalyst, 25 bio-imaging, 26 electrical chemiluminescence etc.…”

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confidence: 99%

“…DA's role is to send the signal from one nerve cell to another cell including the brain pathway. 9 The abnormal secretion level of DA may lead to Parkinson disease, schizophrenia, bipolar disorder, attention hyperactivity disorder and addiction. 10 So, the detection of DA in biological sample is crucial since it plays a vital role in our body.…”

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confidence: 99%

“…As can be seen, the linear range, and LOD of the present method were comparable to those reported by others using graphene, polyvinyl alcohol, tryptophan/graphene, porous graphene oxide/gold nanoparticles, LaMnO 3 and graphene/SPCE modified electrodes. 9,21,49,50 The real-world application of our senor (SPCE/CQD) was also tested in human urine samples spiked with known concentration of (3 μM) DA. For this analysis, CVs were recorded in 0.1 M PBS with the addition of various concentrations of diluted urine samples.…”

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confidence: 99%

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Electrochemically Exfoliated Carbon Quantum Dots Modified Electrodes for Detection of Dopamine Neurotransmitter

Devi

Kumar

Sundramoorthy

2018

J. Electrochem. Soc.

113

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A simple electroanalytical method was developed to detect dopamine (DA) neurotransmitter by using carbon quantum dots (CQDs) modified electrode. To synthesis CQDs, a green electrochemical method was adopted and graphite rods were used as anode and cathodes in 0.1 M NaOH/ethanol (EtOH) as the electrolyte solution. As-synthesized CQD showed different particle sizes depending on the applied current with time as characterized by UV-visible spectroscopy. The particle size, lattice structure and functional groups of CQDs were analyzed by the HR-TEM, XRD and FT-IR, respectively. The CQD exhibited a green fluorescence under UV light (365 nm). Moreover, CQD dispersion was used to modify glassy carbon electrode (GCE) and screen-printed carbon electrode (SPCE) to study their electrochemical and electrocatalytic properties. The both GCE/CQD and SPCE/CQD showed higher electrocatalytic activity toward oxidation of dopamine (DA) in phosphate buffered saline (PBS) solution (pH = 7.4). In order to avoid interferences, Nafion (Nf) layer was coated on the CQD film modified electrode. The effect of scan rate on DA oxidation was studied from 10 to 150 mV/s. The calibration curve was recorded for DA from 1 to 7 μM using a SPCE/CQD and the limit of detection was found to be 0.099 μM. The observed electro-catalytic activity of the CQD was attributed to their negatively charged functional groups which attracted positively charged DA in 0.1 M PBS. In addition, detection of DA in spiked human urine sample was demonstrated with satisfactory recovery analysis.

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confidence: 99%

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confidence: 99%

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confidence: 99%

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Electrochemically Exfoliated Carbon Quantum Dots Modified Electrodes for Detection of Dopamine Neurotransmitter

Devi

Kumar

Sundramoorthy

2018

J. Electrochem. Soc.

113

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“…The incorporation of AgNPs into rGO on GCE offers no improvement in linearity (10-800 lM) and has a negative impact on LOD (9.6 lM). A GCE modified with tryptophan-functionalized graphene exhibits worse LOD (10.09 lM) and linearity (0.2-12.9 mM) [260]. The cobalt tetraphenylporphyrin-chemically reduced graphene/ GCE exhibits linearity of 5-200 lM but its LOD is 1.2 lM [265], compared to 5-1300 lM and 2.2 lM of the nitrogen doped graphene/GCE.…”

Section: Other Small Electroactive Analytesmentioning

confidence: 99%

Recent advances in electrochemical biosensing schemes using graphene and graphene-based nanocomposites

Vashist

Luong

2015

Carbon

214

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“…A significant amount of work also focused on development of graphene-based materials for sensing applications, mostly for detection of bio-relevant molecules, including glucose [14], cytochrome c [145], or dopamine [146,147] although sensors of inorganic molecules such as hydrogen peroxide [148], cadmium [149], or protons/hydronium ions [150] were also successfully fabricated [6].…”

Section: Modification and Doping Of Graphene For Applications In Elecmentioning

confidence: 99%

Electrochemistry of Graphene

Patten¹,

Velický²,

Dryfe³

2015

Advances in Electrochemical Sciences and Engineering

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Simultaneous determination of ascorbic acid, dopamine and uric acid based on tryptophan functionalized graphene

Cited by 176 publications

References 33 publications

Electrochemically Exfoliated Carbon Quantum Dots Modified Electrodes for Detection of Dopamine Neurotransmitter

Electrochemically Exfoliated Carbon Quantum Dots Modified Electrodes for Detection of Dopamine Neurotransmitter

Recent advances in electrochemical biosensing schemes using graphene and graphene-based nanocomposites

Electrochemistry of Graphene

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