Simultaneous determination of dopamine, ascorbic acid and uric acid at poly (Evans Blue) modified glassy carbon electrode

Lin, Lin; Chen, Jinghua; Yao, Hong; Chen, Yuanzhong; Zheng, Yufeng

doi:10.1016/j.bioelechem.2008.01.009

Cited by 186 publications

(67 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…4,5 Dopamine (3,4-dihydroxyphenethylamine) (DA) is a neurotransmitter of the catecholamine family, which is widely distributed in the central nervous system of animals for message transfer from one neuron to another neuron. 6,7 It is derived from l-tyrosine by a series of biochemical reactions using tyrosine hydroxylase and decarboxylase, and it is the precursor to norepinephrine (noradrenaline) and epinephrine (adrenalin). DA is also a hormone that is related to many important functions in the human brain and body.…”

Section: Introductionmentioning

confidence: 99%

Selective detection of dopamine in the presence of ascorbic acid via fluorescence quenching of InP/ZnS quantum dots

An¹,

Kim²,

Ankireddy³

2015

IJN

View full text Add to dashboard Cite

Dopamine is a neurotransmitter of the catecholamine family and has many important roles, especially in human brain. Several diseases of the nervous system, such as Parkinson’s disease, attention deficit hyperactivity disorder, restless legs syndrome, are believed to be related to deficiency of dopamine. Several studies have been performed to detect dopamine by using electrochemical analysis. In this study, quantum dots (QDs) were used as sensing media for the detection of dopamine. The surface of the QDs was modified with l -cysteine by coupling reaction to increase the selectivity of dopamine. The fluorescence of cysteine-capped indium phosphide/zinc sulfide QDs was quenched by dopamine with various concentrations in the presence of ascorbic acid. This method shows good selectivity for dopamine detection, and the detection limit was 5 nM.

show abstract

Section: Introductionmentioning

confidence: 99%

Selective detection of dopamine in the presence of ascorbic acid via fluorescence quenching of InP/ZnS quantum dots

An¹,

Kim²,

Ankireddy³

2015

IJN

View full text Add to dashboard Cite

show abstract

“…The construction of DNA sensors can be formed by either direct absorption or covalent bond of DNA on the top of polymer layer [14][15][16][17]. Although, some papers have reported the determination of neurotransmitter using polymer modified electrodes [18][19][20], limited attention has been towards to the application of this layer-bylayer modified DNA and conducting polymers biosensors for the determination of neurotransmitter. In this work, a voltammetric sensor was fabricated by depositing a layer of DNA onto ethylenediamine (En), which was covalent bonded on a previous polyglutamic acid (PGA) modified glass carbon electrode (GCE) (DNA/En/PGA/GCE).…”

Section: Introductionmentioning

confidence: 99%

Sensitive and Selective Detection of Dopamine Using a DNA Immobilized Ethylenedidamine/Polyglutamic Modified Electrode

Zou

Luo

et al. 2011

Electroanalysis

View full text Add to dashboard Cite

DNA was attached on the surface of an ethylenedidamine/polyglutamic(En/PGA) modified glassy carbon electrode (GCE) to create a novel voltammetric sensor (DNA/En/PGA/GCE) for dopamine (DA). This modified electrode exhibited a linear voltammetric response for DA in the range from 1.0 10 À7 mol L À1 to 1 10 À5 mol L À1 , with a detection limit of 2 10 À8 mol L À1. The detection of DA was found to be unaffected by the presence of ascorbic acid, uric acid, serotonin and folic acid. The method proposed was applied to detect DA in pharmaceutical dosage and human blood serum with good satisfactory results.

show abstract

“…Among these methods, electroanalytical techniques are somewhat more advantageous over other methods [23 -26]. However, an important disadvantage of the electroanalytical technique is the overlapping of the oxidation potential of AA, DA and UA due to homogeneous electron transfer at bare electrodes [1,23]. Therefore, it is essential to develop simple, selective and sensitive methods for the simultaneous determination of ascorbic acid (AA), dopamine (DA) and uric acid (UA) by voltammetric techniques.…”

Section: Introductionmentioning

confidence: 99%

Simultaneous Determination of Ascorbic Acid, Dopamine and Uric Acid at Pt Nanoparticles Decorated Multiwall Carbon Nanotubes Modified GCE

2010

View full text Add to dashboard Cite

A modified electrode was fabricated by electrochemically deposition of Pt nanoparticles on the multiwall carbon nanotube covered glassy carbon electrode (Pt nanoparticles decorated MWCNT/GCE). A higher catalytic activity was obtained to electrocatalytic oxidation of ascorbic acid, dopamine, and uric acid due to the enhanced peak current and well-defined peak separations compared with both, bare and MWCNT/GCE. The electrode surfaces were characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD) and electrochemical impedance spectroscopy (EIS). Individual and simultaneous determination of AA, DA, and UA were studied by differential pulse voltammetry. The detection limits were individually calculated for ascorbic acid, dopamine, and uric acid as being 1.9 Â 10 À5 M, 2.78 Â 10 À8 M, and 3.2 Â 10 À8 M, respectively. In simultaneous determination, LODs were calculated for AA, DA, and UA, as of 2 Â 10 À5 M, 4.83 Â 10 À8 M, and 3.5 Â 10 À7 M, respectively.

show abstract

Simultaneous determination of dopamine, ascorbic acid and uric acid at poly (Evans Blue) modified glassy carbon electrode

Cited by 186 publications

References 22 publications

Selective detection of dopamine in the presence of ascorbic acid via fluorescence quenching of InP/ZnS quantum dots

Selective detection of dopamine in the presence of ascorbic acid via fluorescence quenching of InP/ZnS quantum dots

Sensitive and Selective Detection of Dopamine Using a DNA Immobilized Ethylenedidamine/Polyglutamic Modified Electrode

Simultaneous Determination of Ascorbic Acid, Dopamine and Uric Acid at Pt Nanoparticles Decorated Multiwall Carbon Nanotubes Modified GCE

Contact Info

Product

Resources

About