Simultaneous determination of melamine and related compounds by capillary zone electrophoresis

Highly sensitive detection of melamine based on fluorescence resonance energy transfer between rhodamine B and gold nanoparticles

“…Traditional instrumental methods, such as high performance liquid chromatography (HPLC) [4], liquid chromatographymass spectrometry (LC-MS) [5], gas chromatography-mass spectrometry (GCeMS) [6], enzyme-linked immunosorbent assay (ELISA) [7] and capillary zone electrophoresis (CZE) [8], can meet the need of detecting sensitivity and selectivity. However, most of these techniques require expensive analytical instruments, complicated sample pre-treatment, heavy use of volatile organic solvents, time-consuming detecting process and an experienced operator, so they can hardly fulfill the demand of rapid on-site screening.…”

Synthesis and characterization of hapten-quantum dots bioconjugates: Application to development of a melamine fluorescentimmunoassay

“…involve typically the use of separation techniques, including capillary electrophoresis [7], high-performance liquid chromatography (HPLC) with spectrophotometric detectors [3,8], and liquid or gas chromatography-mass spectrometry [9,10]. Most of such already described methods offer low detection limits in the order of mg kg À 1 but often present some important disadvantages, including complex and time-consuming sample pretreatment, expensive instrumentation, long analysis times, etc.…”

Determination of melamine by flow injection analysis based on chemiluminescence system

“…Up to now, several analytical methods, including high-performance liquid chromatography (HPLC) (Kim et al, 2008;Sun, Wang, Ai, Liang, & Wu, 2010;, liquid chromatography/mass spectrometry (LC/MS) (Filigenzi, Tor, Poppenga, Aston, & Puschner, 2007;Ibanez, Sancho, & Hernandez, 2009;Kim et al, 2008;Sancho, Ibanez, Grimalt, Pozo, & Hernade, 2005), gas chromatography (GC) (Yokley, Mayer, Rezaaiyan, Manuli, & Cheung, 2000), gas chromatography/mass spectrometry (GC/MS) (Li, Qi, & Shi, 2009) and capillary electrophoresis (CE) (Tsai et al, 2009;Xia et al, 2010), have been developed for the detection of melamine in infant formula and milk-based products. However, most of the above methods required expensive and complicated instruments (such as MS) and time-consuming sample pretreatment (such as derivatisation or extraction), which made high throughput, realtime melamine screening difficult .…”