Simultaneous Determination of N,N-Dimethylaniline and Phenol in Wastewater by High-Performance Liquid Chromatography with Chemiluminescence Detection

Liquid-Phase Chemiluminescence Detection for HPLC

“…It was later found that reducing agents, such as corticosteroids, phenols, and anilines, can react with radical intermediates of the light-producing pathway of various luminol systems and therefore influence the rate or efficiency of emission [54][55][56][57]. For post-column detection, the most common approach involves combining the column eluate stream with one solution containing luminol and base, and another containing hexacyanoferrate(III), but the order in which they are merged varies in different procedures [58][59][60][61][62]. A diverse range of other oxidants and catalysts (e.g., 1 2 , Cu(ll)/H 2 0 2 , Bro-, Co(II), and [Cu(HI0 6 ) 2 ]5-) has also been used in procedures based on signal enhancement or inhibition [63][64][65][66][67].…”

Chemiluminescence detection in liquid chromatography: Applications to clinical, pharmaceutical, environmental and food analysis—A review

“…A great advantage over HPLC with UV detection is that the HPLC-CL method allowed the analysis of the samples without an elaborated extraction process to remove potential interfering substances, as these substances do not provide CL signal. A method for the simultaneous determination of N,N-dimethylaniline and phenol in water samples was developed by Huang et al using the luminol-K 3 Fe(CN) 6 system in alkaline medium [109]. These reagents were previously mixed in a T-type mixing device, and the resultant solution was then mixed with the eluent from the column in another T-connector before reaching the detector cell.…”

A High-Performance Liquid Chromatography:Chemiluminescence Method for Potential Determination of Vardenafil in Dietary Supplement

“…The combination of HPLC high resolution, CL sensitive detection and FI manipulation would be one of the plausible techniques for a sensitive, precise, and facile determination of trace levels of compounds in the complex mixture of substances [13]. Recent studies witness rapid progress in HPLC-CL method, which is widely used to perform diverse qualitative and quantitative analytical problems [15–18]. …”