Simultaneous determination of nine perfluoroalkyl carboxylic acids by a series of amide acetals derivatization and gas chromatography tandem mass spectrometry

Comprehensive Strategy for Sample Preparation for the Analysis of Food Contaminants and Residues by GC–MS/MS: A Review of Recent Research Trends

“…Therefore, to separate lipids efficiently, the extract is often deep-frozen, during which a fairly significant amount of non-polar substances are lost [22]. A novel material, namely bond elute enhanced matrix removal (EMR), has a stronger selective adsorption affinity for lipids and has recently been used in the analysis of pesticides in kale, pork, salmon, chicken eggs, and avocado, also used to detect antibacterial drugs in cream disinfection products, specifically adsorbing C5 and long-chain hydrocarbons from lipids [99][100][101].…”

“…The unique physical and chemical characteristics imparted by the fluorinated region of the molecule include water and oil repellency, heat resistance, and surfactant properties, making these compounds suitable for a wide range of industrial and commercial applications. The hardly-degradable characteristic and wide distribution of PFCAs contribute to the persistence of these compounds in the environment and to their bioaccumulation [101]. QuEChERS is the most recommended extraction and separation method for detecting PFCAs [113].…”

Comment on “Release of Volatile Per- and Polyfluoroalkyl Substances from Aqueous Film-Forming Foam”

“…A second set of tubes identical to the first was analyzed by TD-GC-MS in positive and negative chemical (soft) ionization mode, which often preserves the molecular ion. While we observed m / z 331 and 293 (data not shown), we did not observe the molecular ion of PFOA-H/PFOA, which further puts into question the PFOA identification by Roth et al To the best of our knowledge, a derivatization step is needed for the determination of PFCAs by GC-MS. ,− …”