Simultaneous determination of taurine, glucuronolactone and glucuronic acid in energy drinks by ultra high performance liquid chromatography–tandem mass spectrometry (triple quadrupole)

Ricciutelli, Massimo; Caprioli, Giovanni; Cortese, Manuela; Lombardozzi, Antonietta; Strano, Morela; Vittori, Sauro; Sagratini, Gianni

doi:10.1016/j.chroma.2014.08.083

Cited by 17 publications

(7 citation statements)

References 16 publications

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“…e literature reports the taurine concentration in energy drinks from nondetected (ND) to 315.3 mg/100 mL [5,[7][8][9]. e taurine content found in this work agreed with that reported in the literature.…”

Section: Taurine Concentrationsupporting

confidence: 88%

“…Many analytical methods have been developed to quantify taurine and caffeine contents in energy drinks. To quantify taurine, micellar electrokinetic chromatography (MEKC) [5], capillary electrophoresis, UV-Vis spectroscopy [6], nuclear magnetic resonance (NMR) [7], and highperformance liquid chromatography (HPLC) with different detectors [8,9] have been used. To quantify caffeine, different techniques have been used: HPLC [10], gas chromatography (GC), thin layer chromatography, UV-Vis spectroscopy, and NMR [5].…”

Section: Introductionmentioning

confidence: 99%

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Simultaneous Determination of Caffeine and Taurine in Energy Drinks by FT-MIR Spectroscopy Coupled with Multivariate Analysis

González-Vázquez

Meza-Márquez

Gallardo-Velázquez

et al. 2020

Journal of Spectroscopy

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Energy drinks have been studied due to their damaging side effects on the health of their consumers when consumed in excess or when combined with alcohol. Our objective was to develop chemometric models, based on Fourier-transform mid-infrared (FT-MIR) spectroscopy, to quantify the taurine and caffeine content in energy drinks rapidly and simultaneously. The taurine and caffeine content in the 50 samples ranged between 0 and 69.51 mg/100 mL and 14.92 and 1126.17 mg/100 mL, respectively. The best prediction model was obtained with the partial least squares (PLS1) algorithm; for taurine, the following values were obtained: determination coefficient of calibration (Rc2) = 0.9999, standard error of calibration (SEC) = 0.15, determination coefficient of validation (Rv2) = 0.9997, and standard error of prediction (SEP) = 0.16; for caffeine, Rc2 = 0.9999, SEC = 0.26, Rv2 = 0.9999, and SEP = 0.32. The model developed with PLS1 showed certainty in predictions during the validation stage and during application to external samples. FT-MIR coupled to chemometrics is a reliable and fast technique (compared to conventional techniques) to quantify taurine and caffeine in energy drinks simultaneously.

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Section: Taurine Concentrationsupporting

confidence: 88%

Section: Introductionmentioning

confidence: 99%

Simultaneous Determination of Caffeine and Taurine in Energy Drinks by FT-MIR Spectroscopy Coupled with Multivariate Analysis

González-Vázquez

Meza-Márquez

Gallardo-Velázquez

et al. 2020

Journal of Spectroscopy

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“…Quantitative analysis of NANA in human plasma was performed without labeling by an LC–MS/MS system, using NANA‐d 3 as a standard, on an XBridge Amide and Atlantis HILIC silica columns . GlcA was less retained on a native silica column, but separated from the corresponding lactone , while on amide columns, NANA and Neu5Gc were the most retained compounds, and GlcA was less retained than these sialic acids . ZIC‐HILIC column was used to analyze metabolites in fermentation broth from β‐lactam antibiotics production, Penicillin and Cephalosporin.…”

Section: Analysis Of Monosaccharidesmentioning

confidence: 99%

Hydrophilic interaction chromatography for the analysis of biopharmaceutical drugs and therapeutic peptides: A review based on the separation characteristics of the hydrophilic interaction chromatography phases

Ikegami

2019

J of Separation Science

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Applications of hydrophilic interaction chromatography for the analysis of biopharmaceutical drugs, i.e., glycosylated proteins represented by monoclonal antibodies are discussed in the manner of glycoproteomics. They can be analyzed using hydrophilic interaction chromatography in five different stages as (1) their intact forms, (2) their subunits, (3) N‐ and O‐glycopeptides digested by proteases, (4) N‐ and O‐glycans released from the glycoproteins or glycopeptides, and (5) monosaccharides. Hydrophilic interaction chromatography is a more useful tool in the order of (1) to (5). At the stages (4) and (5), quantitation of glycans and saccharides are also reported. Hydrophilic interaction chromatography is employed not only for analytical uses, but also pretreatment items as solid phase extraction, followed by reversed‐phase liquid chromatography separations. Comprehensive search results of these application of hydrophilic interaction chromatography are summarized in tables to show what kind of hydrophilic interaction chromatography columns are suitable for each step of analysis.Relationship of favored and less favored hydrophilic interaction chromatography columns and their separation characteristics such as hydrophilicity, and selectivity for structural difference, is also discussed. Analysis of the therapeutic peptides (not glycosylated) using hydrophilic interaction chromatography is summarized, too.

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“…Caffeine and taurine were simultaneously determined by Chirita et al in energy drinks using hydrophilic interaction chromatography with UV and evaporative light scattering detection [15]. Ricciutelli et al provided an ultraperformance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) method for analyzing taurine in energy drinks without derivatization [16]. Al-Bratty et al determined caffeine in commercial energy beverages by using Gas chromatography-mass spectrometry (GC-MS) [17].…”

Section: Introductionmentioning

confidence: 99%

Quick and simultaneous determination of caffeine and taurine in beverages using UPLC-ESI-MS

et al. 2021

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A rapid UPLC-ESI-MS method was developed for simultaneous determination of caffeine and taurine in beverages (energy drinks and soft drinks). The molecular ions of caffeine and taurine were identified in single ion recording mode at m/z 194.98 and 125.86, respectively. The mass spectrometer parameters were optimized as: capillary voltage 3.0 kV, cone voltage 35 V, extractor 3 V, RF Lens 0.1 V, source temperature 150 °C, desolvation temperature 350 °C, nitrogen 600 L/h, LMR1 7.9, HMR1 15.2, IE1 0.30. The mobile phase comprising methanol (0.1% formic acid) (A) and water (5 mM ammonium acetate) (B) was used in gradient mode. The mobile phase components A and B were pumped in 80:20 (v:v) ratio from 0-0.44 min, and then 100% of component A was pumped between 0.45-0.68 min, and at 0.69 min the composition was returned to 80:20 (v:v) ratio of A and B till 2.0 min. Caffeine and taurine were eluted at 0.46 and 0.43 min, respectively. The samples of energy drinks and soft drinks were diluted in a solvent system comprising methanol and water in 80:20 (v:v) ratio. Our investigations showed that soft drinks SD1 and SD2 have 88.8±4.2% and 110.7±3.6% (w:w) caffeine of their labeled claim. The caffeine content in energy drink brands ED1, ED2, ED3, and ED4 was 76.9±2.5, 65.6±3.4, 88.1±12.6, and 89.1±2.8% (w:w) of labeled claims, respectively. While taurine content in ED1, ED2, ED3, and ED4 was 86.5±8.4, 81.3±27.5, 101.9±4.8, and 97.1±0.3% (w:w) of labeled claim, respectively.

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Simultaneous determination of taurine, glucuronolactone and glucuronic acid in energy drinks by ultra high performance liquid chromatography–tandem mass spectrometry (triple quadrupole)

Cited by 17 publications

References 16 publications

Simultaneous Determination of Caffeine and Taurine in Energy Drinks by FT-MIR Spectroscopy Coupled with Multivariate Analysis

Simultaneous Determination of Caffeine and Taurine in Energy Drinks by FT-MIR Spectroscopy Coupled with Multivariate Analysis

Hydrophilic interaction chromatography for the analysis of biopharmaceutical drugs and therapeutic peptides: A review based on the separation characteristics of the hydrophilic interaction chromatography phases

Quick and simultaneous determination of caffeine and taurine in beverages using UPLC-ESI-MS

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