Simultaneous HPLC-PDA determination of commonly prescribed antidepressants and caffeine in sludge from sewage treatment plants and river sediments in the Itaipu reservoir region, Paraná, Brazil

Bioaccumulation potential of the tricyclic antidepressant amitriptyline in a marine Polychaete, Nereis virens

“…The concentrations of amitriptyline detected were within the range of those previously reported in sediment collected from estuarine, marine, and freshwater systems. Sediment samples from a Baltic Sea estuary ranged from 0.7 to 25.1 ng/g dry wt (Kucharski et al, 2022), between <0.10 to 0.40 ng/g amitriptyline dry wt in marine sediment samples collected in the Bay of Cádiz (Maranho et al, 2015), and up to 80 ng/g dry wt in river sediment samples receiving WWTP discharge in the Itaipu reservoir region, Brazil (Costa Junior et al, 2020). In polychaetes, the body burden concentration of amitriptyline was below the LOD in those exposed to sediment collected from Kvitsøy and IVAR, and present at measurable concentrations, 5.2 ± 2.8 ng/g, in sediment collected from Boknafjord (Fig.…”