Simultaneous Kinetic‐Potentiometric Determination of Hydrazine and Thiosemicarbazide by Partial Least Squares and Principle Component Regression Methods

Abstract

Simultaneous determination of hydrazine (HZ) and thiosemicarbazide (TSC) by partial least squares (PLS) and principle component regression (PCR) was carried out based on kinetic data of novel potentiometry. The rate of chloride ion production in reaction of HZ and TSC with N‐chlorosuccinimide (NCS) was monitored by a chloride ion‐selective electrode. The experimental dada shows not only the good ability of ion‐selective electrodes (ISEs) as detectors for the direct determination of chloride ions but also for simultaneous kinetic‐potentiometric analysis using chemometrics methods. The methods are based on the difference observed in the production rate of chloride ions. The results show that simultaneous determination of HZ and TSC can be performed in their concentration ranges of 0.7‐20.0 and 0.5‐20.0 μg mL−1, respectively. The total relative standard error for applying PLS and PCR methods to 9 synthetic samples in the concentration ranges of 0.8‐10 μg mL−1 of TSC and 1.0‐12.0 μg mL−1 of HZ was 4.62 and 4.98, respectively. The effects of certain foreign ions upon the reaction rate were determined for the assessment of the selectivity of the method. Both methods (PLS and PCR) were validated using a set of synthetic sample mixtures and then applied for simultaneous determination of HZ and TSC in water samples.

Etching-based transformation of dumbbell-shaped gold nanorods facilitated by hexavalent chromium and their possible application as a plasmonic sensor

“…The tolerance limit of the system towards interferents was determined based on the maximum concentration of added ions that can cause less than 5% relative error. 33 The sensor response was found to be negligible with most of the interferents (Fig. 5).…”

Application of H-Point Standard Addition Method and Multivariate Calibration Methods to the Simultaneous Kinetic-Potentiometric Determination of Cerium(IV) and Dichoromate

“…Using the standard analyte solutions, we can construct a calibration graph of (10 ∆E/S -1) versus concentration (fixed-time method) [22][23][24][25][26][27], where ∆E is the potential variation in a selected time interval ∆t and S is the slope of the fluoride electrode response, which is determined periodically by successive additions of micro-amounts of 100 µL of 1.0 × 10 -5 -1.0 mol/L of NaF standard solutions in 25 mL of water mixed with 2 mL of buffer solution.…”

“…In the field of potentiometry, several methods have been reported based on flow injection system and titration using PLS, ANN and Kalman filter as modeling methods [17][18][19][20][21]. We are reported the first application of PLS and PCR multivariate calibration methods and HPSAM to the simultaneous kinetic-potentiometric determination of binary mixtures of hydrazine and its derivatives [22,23] and binary mixture of levodopa and carbidopa drugs [24]. The methods were based on the differences observed in the production rate of chloride ions in reaction of these species with N-chlorosuccinimide.…”

A Simple and Highly Sensitive Method for Quantitative Detection of Methyl Paraben and Phenol in Cosmetics Using Derivative Spectrophotometry and Multivariate Chemometric Techniques

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