Simultaneous measurement of seminal L-carnitine, α,1-4-glucosidase, and glycerylphosphorylcholine in azoospermic and Oligozoospermic patients

Casano, Rosaria; Orlando, Claudio; Caldini, Anna; Barni, Tullio; Natali, Alessandro; Serio, Mario

doi:10.1016/s0015-0282(16)50013-2

Cited by 34 publications

(21 citation statements)

References 17 publications

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“…Semen analysis with biochemical markers is of great diagnostic value, azoospermia with abnormally low semen volume, acidic pH, very low or indetectable fructose level (which is produced by seminal vesicles) is a characteristic finding in patients affected by CBAVD. Low levels of seminal a-glucosidase, the most common epididymal marker, are present in CBAVD, in men with epididymal obstruction but also in some men with azoospermia due to tubular damage (Casano et al 1987). FSH and LH are normal.…”

Section: Infertility Due To Impairment Of Sperm Transport And/or Accementioning

confidence: 99%

Clinical Aspects of Male Infertility

Krausz

Forti

2000

Results and Problems in Cell Differentiation

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Section: Infertility Due To Impairment Of Sperm Transport And/or Accementioning

confidence: 99%

Clinical Aspects of Male Infertility

Krausz

Forti

2000

Results and Problems in Cell Differentiation

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“…Others have reported a decrease in NAG activity as sperm abnormality increases [Casano et al 1987;Pena et al 2004;Rivas et al 1981;Viljoen et al 1990]. Individuals with low NAG activity also exhibited poor ability to bind the zona pellucida, suggesting that NAG may have a role in sperm-egg binding [Ben Ali et al 1994].…”

Section: Introductionmentioning

confidence: 99%

The Relevance of Neutral α-Glucosidase Activity in Andrology

Levrant

Watanabe²,

Land

et al. 2009

Systems Biology in Reproductive Medicine

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To assess the usefulness of routine determination of neutral a-glucosidase (NAG) in andrology, 216 ejaculates were analyzed for NAG activity and semen quality. A correlation between NAG activity and semen volume and sperm concentration was determined; however, no correlation was observed between NAG activity and sperm motility or sperm morphology. The number of azoospermic ejaculates that had NAG activity below acceptable levels was significantly higher than the number of non-azoospermic ejaculates with similarly low NAG levels. Routine determination of NAG activity is not practical; however, when an epididymal pathology leading to a physiological or anatomical functional alteration is suspected, the determination of NAG activity is a valuable tool in the diagnosis, and would also aid in the prognosis.

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“…The most intensively studied phospholipid was glycerophosphorylcholine, and its epididymal origin has been clearly shown (Casano et al, 1987). They are found in larger numbers in the second fraction of the ejaculate and are found in smaller numbers in vasectomized subjects.…”

Section: Results Discussionmentioning

confidence: 99%

On the glandular origin of seminal plasma lipids in man

et al. 2009

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The aim of this study is to examine the glandular origin of seminal fluid lipids in man. The triglycerides, the total cholesterol, the non-esterified fatty acid and the total phospholipids were measured in seminal plasma of vasectomized patients ( n = 8 ) and control subjects ( n = 15). The same parameters were measured in seminal plasma collected in three fractions from split ejaculates ( n = 10).The total cholesterol and the non-esterified fatty acid are principally prostatic in origin. The phospholipids are secreted by the epididymis but also by the prostrate. The origin of the triglycerides seems to be very varied.

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Simultaneous measurement of seminal L-carnitine, α,1-4-glucosidase, and glycerylphosphorylcholine in azoospermic and Oligozoospermic patients

Cited by 34 publications

References 17 publications

Clinical Aspects of Male Infertility

Clinical Aspects of Male Infertility

The Relevance of Neutral α-Glucosidase Activity in Andrology

On the glandular origin of seminal plasma lipids in man

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