Simultaneous microemulsion liquid chromatographic analysis of fat-soluble vitamins in pharmaceutical formulations: Optimization using genetic algorithm

Modeling and optimization of activated sludge bulking for a real wastewater treatment plant using hybrid artificial neural networks-genetic algorithm approach

“…The GA has been broadly applied for optimization in complex spaces of different scientific disciplines (Sahoo and Ray, 2006). The GA can obtain acceptable results (maximize or minimize) using operators such as creating population, selection, crossover and mutation (Momenbeik et al, 2010).…”

Development of chitosan nanoparticles as drug delivery system for a prototype capsid inhibitor

“…Experimental design help the researchers to estimate the main and interaction of variables for the simultaneous optimization and investigation of variables effect with at least experiments (Momenbeik et al, 2010). Influence of important variables (Bay41-4109, chitosan and TPP concentrations) were investigated and optimized by central composite design (CCD) combined with response surface methodology (RSM).…”

Determination of the lipophilicity of Salvia miltiorrhiza Radix et Rhizoma (danshen root) ingredients by microemulsion liquid chromatography: optimization using cluster analysis and a linear solvation energy relationship‐based method

“…Microemulsion liquid chromatography (MELC) is a relatively new chromatographic technique that uses a microemulsion as a mobile phase using conventional columns. MELC has been used for the separation of mixtures of test solutes or pharmaceutical compounds by an isocratic system (Berthod and De, ; El‐Sherbiny et al ., ; Jančić et al ., ), and for the investigation of drugs in their pharmaceutical preparations (McEvoy et al ., ; Momenbeik et al ., ; Althanyan et al ., ) or in biological samples (Jancic et al ., ; Walash et al ., ). Recently, MELC has also been used to mimic several biologically important processes (Liu et al ., ) and predict the n‐ octanol–water partition coefficient (Li et al ., ).…”