Simultaneous presentation of meningiomas with other intracranial tumours

Abstract

Fifteen patients with simultaneous presentation of meningiomas with other intracranial tumours are reviewed. The associated tumours included a brain metastasis in six cases, glioma in three, pituitary adenoma in two, craniopharyngioma in one,acoustic schwannoma in two and brain lymphoma in one. A correct preoperative radiological diagnosis was made in 12 patients; in three others the associated tumour was discovered at operation and by histological studies. A one-stage removal of both tumours through the same approach was performed in nine patients, whereas six others underwent two-stage operations with an interval of 1 - 13 months. The literature relating to meningiomas associated with other intracranial tumours is reviewed and the possible pathogenetic correlations are discussed. A diagnostic pitfall may occur for metastasis into a meningioma, glioma surrounding a meningioma and different suprasellar lesions. The surgical indication and management of meningiomas may be significantly influenced by the presence of another different intracranial tumour.

First report of the simultaneous occurrence of choroid plexus papilloma and meningioma in a dog

“…Meningiomas are the tumour type more often found in cases of multiple intracranial tumours of different histology in humans (Spallone et al, 1991;Davis et al, 1995;Maiuri et al, 2005). This is due both to the frequent occurrence of even incidental intracranial meningiomas and to their long clinical evolution before diagnosis.…”

“…This is due both to the frequent occurrence of even incidental intracranial meningiomas and to their long clinical evolution before diagnosis. Thus, they have an increased probability of simultaneously harbouring another primary or secondary tumour (Maiuri et al, 2005). In a recent review of meningiomas associated with other tumours of different origin in humans, authors observed that the most frequent combinations were those of meningioma and brain metastasis, meningioma and glioma, and meningioma and pituitary adenoma (Maiuri et al, 2005).…”

“…As a result of modern imaging techniques, the diagnosis of cerebral neoplasia is increasing and therefore, the actual incidence is probably unknown (Bagley et al, 1999;Snyder et al, 2006). In human medicine, an association of multiple primary intracranial tumours of different histological types not relating to radiotherapy or phacomato-ses is a rare event (Maiuri et al, 2005;Tugcu et al, 2006). An annual incidence in the general population can be expected to be much less than 1 per million, solely based on the annual incidence rates of 10-15 cases per 100,000 who develop primary brain tumours (Zülch, 1986;Hassad and Al-Mefty, 1996).…”

“…These authors reported an oligodendroglioma and a meningioma (Stacy et al, 2003), a meningioma and an astrocytoma (Snyder et al, 2006), and a medulloblastoma and an astrocytoma (Mackillop et al, 2007) arising simultaneously at separate sites in the brain. The associations of meningioma and glioma, meningioma and brain metastases and meningioma and pituitary adenoma were found to be the most common in different studies in humans (Davis et al, 1995;Goyal et al, 2003;Maiuri et al, 2005). Although meningioma has been associated with nine different types of intracranial tumours, the association of meningioma and choroid plexus papilloma has never been reported, to the best of the author's knowledge, either in human or in veterinary medicine (Stacy et al, 2003;Maiuri et al, 2005;Alves et al, 2006;Banka et al, 2007).…”

“…The associations of meningioma and glioma, meningioma and brain metastases and meningioma and pituitary adenoma were found to be the most common in different studies in humans (Davis et al, 1995;Goyal et al, 2003;Maiuri et al, 2005). Although meningioma has been associated with nine different types of intracranial tumours, the association of meningioma and choroid plexus papilloma has never been reported, to the best of the author's knowledge, either in human or in veterinary medicine (Stacy et al, 2003;Maiuri et al, 2005;Alves et al, 2006;Banka et al, 2007). This short communication describes the clinical, neuroimaging and pathological features of a spontaneously occurring meningioma and choroid plexus papilloma arising simultaneously in separate sites in the brain of a dog.…”