Simultaneous Separation and Determination of 22 Coumarin Derivatives in Cosmetics by UPLC-MS/MS

Ma, Qiang; Xi, Hailing; Ma, Heng; Meng, Xianshuang; Wang, Ziming; Bai, Hua; Li, Wentao; Chao, Wang

doi:10.1007/s10337-014-2841-3

Cited by 23 publications

(13 citation statements)

References 25 publications

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“…Thus, with lower LOQs, the developed method is suitable for coumarin determination (for other derivatives, there are no limits) in deodorants and antiperspirants of all types including fragranced body sprays (Guidance for the use of IFRA standards, 2019; EU Council Directive No 76/768/EEC). LOQs of coumarins in this study was lower than those reported in literature (32-45 ng mL -1 for simple coumarins by HPLC-DAD (Xiongfeng et al,20l6); 0.17 mg kg -1 for 6-methylcoumarin by HPLC-DAD, 5.0 mg kg -1 by GC-FID (Liu et al, 2018)), although the LOQs obtained by fluorescence detection are slightly higher than that obtained by the HPLC-MS/MS methods (0.5-2 ng mL -1 for 22 coumarin derivatives (Ma et al, 2015)). The recovery values of 70-97 % were obtained (RSD % 4.1-6.4) for sample 3 spiked with two substances concentration levels, confirming the applicability and good precision of the presented method.…”

Section: Methods Validationmentioning

confidence: 99%

“…A mixture of an organic solvent and aqueous acid solution with gradient elution is often chosen as the mobile phase. A spectrophotometric detector, fluorescent detector (Hroboňová et al, 2013) or a mass spectrometric detector (Ma et al, 2015) are used to detect coumarins. An important part of chemical analysis is the preparation of samples to remove interferences from the matrix and to obtain a fraction of the sample or the final analyte extract in a solvent compatible with the analytical technique used, e.g.…”

Section: Introductionmentioning

confidence: 99%

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Application of selective polymeric sorbents for simple coumarins extraction from deodorant samples

Hroboňová

Špačková

2020

Acta Chimica Slovaca

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Coumarins (2H-1-benzopyran-2-coumarin derivatives) are derivatives of cinnamic acid naturally occurring in many plants, fungi, and fruits. They are used as ingredients in cosmetics to enhance the aroma and other biological effects. In this work, cosmetic samples (deodorants) were treated by solid phase extraction prior to high performance liquid chromatography determination of coumarins. Traditional sorbent (C18) and selective polymer-based sorbents (laboratory prepared and commercial) were used for solid phase extraction. Recovery values were above 85 % (RSDs below 6 %) except for esculin, where the recovery was lower. Core-shell column of C18 type and gradient of mobile phase methanol—1 % acetic acid were used for high performance liquid chromatography analysis of extracts. Limits of quantitation were 0.5 µg mL−1 for coumarin (ultraviolet detection) and below 12 ng mL−1 for esculin, umbelliferonene, scoparone, 4-methylumbelliferone, herniarin (fluorescence detection). In the tested samples, no coumarins were detected.

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Section: Methods Validationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Application of selective polymeric sorbents for simple coumarins extraction from deodorant samples

Hroboňová

Špačková

2020

Acta Chimica Slovaca

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“…Afterwards, analytes are recovered by elution in a solvent [ 78 ]. However, its application to cosmetics analysis usually requires a previous sample pre-treatment, mainly performed by simple dilution in water [ 42 , 45 , 50 ] or an organic solvent such as MeOH to obtain a liquid phase [ 43 , 46 ]. Undoubtedly, the sorbent selection is critical to obtain a successful SPE method since it plays an important role in the efficiency and analyte selectivity.…”

Section: Sample Preparation Strategies For Cosmetics Analysismentioning

confidence: 99%

“…The commercial reversed-phase water-wettable polymer N-vinylpyrrolidone-DVB sorbent, commonly known as Oasis HLB ® , presents a hydrophilic–lipophilic balance, thus it can be used for acidic, basic and neutral analytes. Oasis HLB ® has been employed to extract coumarin derivatives from cosmetics [ 43 ]. Analysis was performed by LC–MS/MS, obtaining recoveries between 80 and 93% and LODs lower than 20 ng g −1 .…”

Section: Sample Preparation Strategies For Cosmetics Analysismentioning

confidence: 99%

Recent Advances in Sample Preparation for Cosmetics and Personal Care Products Analysis

et al. 2021

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The use of cosmetics and personal care products is increasing worldwide. Their high matrix complexity, together with the wide range of products currently marketed under different forms imply a challenge for their analysis, most of them requiring a sample pre-treatment step before analysis. Classical sample preparation methodologies involve large amounts of organic solvents as well as multiple steps resulting in large time consumption. Therefore, in recent years, the trends have been moved towards the development of simple, sustainable, and environmentally friendly methodologies in two ways: (i) the miniaturization of conventional procedures allowing a reduction in the consumption of solvents and reagents; and (ii) the development and application of sorbent- and liquid-based microextraction technologies to obtain a high analyte enrichment, avoiding or significantly reducing the use of organic solvents. This review provides an overview of analytical methodology during the last ten years, placing special emphasis on sample preparation to analyse cosmetics and personal care products. The use of liquid–liquid and solid–liquid extraction (LLE, SLE), ultrasound-assisted extraction (UAE), solid-phase extraction (SPE), pressurized liquid extraction (PLE), matrix solid-phase extraction (MSPD), and liquid- and sorbent-based microextraction techniques will be reviewed. The most recent advances and future trends including the development of new materials and green solvents will be also addressed.

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“…Although classical LLE and solid–liquid extraction (SLE) are broadly used in cosmetic analysis , the simpler, faster and greener procedures are being developed. Solvent extraction (SE) approach for isolating organic substances have turned into ultrasound‐assisted extraction (USAE) , accelerated SE , dispersive liquid–liquid microextraction (DLLME) , SPE , matrix solid‐phase dispersion (MSPD) , and SPME . Classical distillation for separating volatile organic compounds from sample matrices has been grown into rapid distillation , and further replaced by purge and trap , headspace single‐drop microextraction (HS‐SDME) or headspace SPME (HS‐SPME) .…”

Section: Introductionmentioning

confidence: 99%

Current trends in sample preparation for cosmetic analysis

Zhong

2016

J of Separation Science

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The widespread applications of cosmetics in modern life make their analysis particularly important from a safety point of view. There is a wide variety of restricted ingredients and prohibited substances that primarily influence the safety of cosmetics. Sample preparation for cosmetic analysis is a crucial step as the complex matrices may seriously interfere with the determination of target analytes. In this review, some new developments (2010-2016) in sample preparation techniques for cosmetic analysis, including liquid-phase microextraction, solid-phase microextraction, matrix solid-phase dispersion, pressurized liquid extraction, cloud point extraction, ultrasound-assisted extraction, and microwave digestion, are presented. Furthermore, the research and progress in sample preparation techniques and their applications in the separation and purification of allowed ingredients and prohibited substances are reviewed.

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Simultaneous Separation and Determination of 22 Coumarin Derivatives in Cosmetics by UPLC-MS/MS

Cited by 23 publications

References 25 publications

Application of selective polymeric sorbents for simple coumarins extraction from deodorant samples

Application of selective polymeric sorbents for simple coumarins extraction from deodorant samples

Recent Advances in Sample Preparation for Cosmetics and Personal Care Products Analysis

Current trends in sample preparation for cosmetic analysis

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