Simultaneous Squamous Carcinoma and Adenocarcinoma of the Larynx

Rm, Komorn; Re, Fechner; Br, Alford; Ja, Ramey; Stiernberg, Charles M.

doi:10.1001/archotol.1973.00780010432017

Cited by 15 publications

(8 citation statements)

References 11 publications

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“…The nonpulmonary PMTs were most often located in the head and neck, skin, and colon, 3,7,25 with lung cancer occurring in 10 to 15 per cent of patients with laryngeal cancer alone 28 …”

Section: Discussionmentioning

confidence: 99%

Multiple Primary Malignant Tumors (MPMT): Study of 68 Autopsy Cases (1963–1980)

Lee

Myers

Scharyj

et al. 1982

J American Geriatrics Society

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Review of 8428 autopsies (1870 for known cancer) showed that 68 patients had had multiple primary malignant tumors (MPMT). Those 68 cases represented 0.8 per cent of all autopsies done, 3.6 per cent of all cancer autopsies. Diagnosis of MPMT was made only at autopsy in 24 cases (35.3 per cent). Thirty-six patients were male, 32 female. Their average age was 64 +/- 2.3 years. Cancers were "synchronous" (diagnosed within a six-month period) in 15 patients, "metachronous" (diagnosed at greater than six-month intervals) in 49, and "combined" in four. Metastatic foci were seen in 53 patients. Fifty-nine patients had two primary malignant tumors (PMTs); seven had three PMTs; one had four PMTs; and one had five PMTs, for a total of 148 tumors. Over half (53.1 per cent) of the second PMTs occurred within five years of the first PMTs. First PMTs were most common in the hematopoietic system and the cervix; second PMTs were most common in the lungs and the hematopoietic system. Second PMTs were less well differentiated than index PMTs. Forty-four deaths had not been directly tumor-related. Nineteen patients with metachronous MPMT lived more than ten years. Of 23 patients with one pulmonary PMT, 22 died within two years. Concomitant findings of pulmonary artery embolism, gallstone(s), thyroid or prostatic hyperplasia, and benign tumor were common in these patients. It is hoped that accumulation of data from this and other series of MPMT will provide insight into the clinicopathologic characteristics, the causes, and the interrelationships of these lesions that constitute primarily a disease of the elderly.

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“…The nonpulmonary PMTs were most often located in the head and neck, skin, and colon, 3,7,25 with lung cancer occurring in 10 to 15 per cent of patients with laryngeal cancer alone 28 …”

Section: Discussionmentioning

confidence: 99%

Multiple Primary Malignant Tumors (MPMT): Study of 68 Autopsy Cases (1963–1980)

Lee

Myers

Scharyj

et al. 1982

J American Geriatrics Society

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“…Synchronous laryngeal SCC and adenocarcinoma were observed by Komorn et al 10 and Obermayer and Ramadan. 11 Eusebi et al 12 and Ferlito 13 reported three cases of synchronous SCC and oat cell carcinoma of the larynx.…”

Section: Discussionmentioning

confidence: 83%

Simultaneous tumours of the larynx with the same histology: a case report and review of the literature

et al. 2005

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Synchronous laryngeal malignancies are extremely uncommon. To the best of our knowledge, only four cases of primary synchronous squamous cell carcinoma (SCC) of the larynx are available in the literature. We report the case of a 52-year-old patient with simultaneous spindle-cell carcinoma and SCC in situ of the larynx. The pathogenesis, treatment and prognosis of this rare occurrence have been discussed.

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“…To the best of our knowledge, only 23 such cases have been previously reported in the literature (table). 5,8,[11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27] Of these, only 1 involved the hypopharynx alone 17 and 1 involved the larynx and hypopharynx. 22 The histogenesis of MFH differs greatly from that of SCC.…”

Section: Discussionmentioning

confidence: 99%

Lingual Hamartoma Associated with a Cleft Palate in a Newborn

2014

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A hamartoma is a benign malformation of native tissue that may occur in any area of the body. Hamartoma of the tongue is a rare developmental lesion. We describe the case of a pendulant lingual hamartoma in a 2-day-old girl that had not been identified on prenatal ultrasonography. We also review the utility of prenatal imaging options, the role of preoperative imaging, the mechanical relationship between lingual hamartoma and cleft palate, the histopathology of this tumor, surgical treatment, and emergency airway management.

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Simultaneous Squamous Carcinoma and Adenocarcinoma of the Larynx

Cited by 15 publications

References 11 publications

Multiple Primary Malignant Tumors (MPMT): Study of 68 Autopsy Cases (1963–1980)

Multiple Primary Malignant Tumors (MPMT): Study of 68 Autopsy Cases (1963–1980)

Simultaneous tumours of the larynx with the same histology: a case report and review of the literature

Lingual Hamartoma Associated with a Cleft Palate in a Newborn

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