Simultaneous Transepithelial Topography-Guided Photorefractive Keratectomy and Accelerated Cross-Linking in Keratoconus: 2-Year Follow-Up

Ahmet, Sibel; Ağca, Alper; Yaşa, Dilek; Koç, Ahmet Alperen; Togac, Mesut; Yıldırım, Yusuf; Yıldız, Burçin Kepez; Demirok, Ahmet

doi:10.1155/2018/2945751

Cited by 18 publications

(18 citation statements)

References 24 publications

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“…16 Sibel Ahmet et al study had 65.0% male and 35.0% female. 15 These studies had a similar result with this study.…”

Section: Discussionsupporting

confidence: 88%

“…14 In a study by Sibel Ahmet, the mean age was 26±5 years (min: 18 years; max: 39 years). 15 These studies had a nearer result with this study.…”

Section: Discussionsupporting

confidence: 52%

“…17 In a study by Sibel Ahmet et al, UCVA was 0.77±0.40 before CXL. 15 According to Siamak et al study, pre-CXL UCVA was 0.72±0.02. 18 UCVA was reduced in the first week of post-CXL.…”

Section: Discussionmentioning

confidence: 94%

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Visual improvement after corneal collagen cross-linking in keratoconus

Sultana¹,

Kadir²,

Hassan³

et al. 2022

IJCEO

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This study was carried out to evaluate the effect of corneal collagen cross-linking on visual acuity, astigmatism and topographic readings (K1, K2, Kapex). : A nonrandomized noncontrolled clinical study was conducted in two tertiary eye centres in Bangladesh from July 2017 to June 2019. All attending patients diagnosed with Keratoconus were included in this study according to selection criteria. Patients with a corneal thickness of fewer than 400 microns, previous viral infection, cornea scarring, corneal opacification, severe ocular surface disease, history of immune disorders, pregnancy, and breastfeeding were excluded from the study. All selected patients underwent collagen cross-linking with Riboflavin and Ultraviolet A, followed up five days, one and six months following the procedure. Visual acuity, topographic readings (K1, K2, Kapex) and cylindrical values were assessed on every visit. The mean value of visual acuity was compared statistically with the baseline value.: A total of 30 eyes of 30 patients were studied in this study. The male-to-female ratio was 2:1. The Mean age (± SD) of the study subjects was 22.7±7.10. Before CXL, the Mean uncorrected visual acuity (UCVA) ±SD was 0.86±.35. In post-CXL follow-up time, the mean UCVA±SD was 0.46±.23 after six months of CXL. Before CXL, the Mean BCVA±SD was 0.35±.22. In post CXL era, the Mean ± SD BCVA was 0.14±.13 after six months of CXL. The Mean K1±SD was 45.66±3.43 before CXL, and the result changed after CXL. The Mean K1±SD was 43.29±3.29 after six months of CXL. The Mean K2±SD was 50.22±5.93 before CXL, and the result differed after six months of CXL. The Mean Kapex ±SD was 54.50±7.38 before CXL, and that was 51.32±6.93 after six months of CXL. Keratoconus is a bilateral non-inflammatory disorder progressively leading to vision-threatening ocular morbidity. Collagen cross-linking improves visual and topographic findings– K1, K2, and Kapex and reduces astigmatism. Early diagnosis of Keratoconus and prompt treatment will help achieve better vision.

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“…16 Sibel Ahmet et al study had 65.0% male and 35.0% female. 15 These studies had a similar result with this study.…”

Section: Discussionsupporting

confidence: 88%

“…14 In a study by Sibel Ahmet, the mean age was 26±5 years (min: 18 years; max: 39 years). 15 These studies had a nearer result with this study.…”

Section: Discussionsupporting

confidence: 52%

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Visual improvement after corneal collagen cross-linking in keratoconus

Sultana¹,

Kadir²,

Hassan³

et al. 2022

IJCEO

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“…Six months follow-up was achieved to protect the visual prognosis and assess the overall corneal parameters. 7 The patient was satisfied with the visual outcome of comfortable distance vision.…”

Section: Rubbing Of Eyesmentioning

confidence: 82%

A cutting-edge refractive surgery treatment option for Forme Frust keratoconus

Shah¹,

Wali²

2022

AOVS

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Forme Fruste keratoconus is a keratoectatic condition of keratoconus that is a rare, unilateral subclinical, abortive, and unusual syndrome. This case outlined a brief discussion of moderate cornea deformation due to mechanical form by prolonged contact lens use dominantly in one eye. It showed topography’s efficacy in discriminating clinical indices to determine corneal mild ecstatic condition, mainly by a practioner. Forme Fruste keratoconus associated with the mild refractive error may benefit from refractive surgery. Meticulous care must be considered before evaluating the preliminary examination of refractive surgery.

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“…Topography-guided PRK can raise a safety issue because it aims to normalize the cornea and a greater ablation depth occurs at the steepest and thinnest point of the cornea [29, 30]. Non-topography-guided PRK may be an option in cases of mild keratoconus with good CDVA to limit the ablation depth [29, 31]. However, topography-guided PRK can normalize the corneal shape, and it can be more effective in correcting HOA.…”

Section: Discussionmentioning

confidence: 99%

One-Year Efficacy and Safety of Combined Photorefractive Keratectomy and Accelerated Corneal Collagen Cross-Linking after Intacs SK Intracorneal Ring Segment Implantation in Moderate Keratoconus

Koh¹,

Seo

Park³

et al. 2019

BioMed Research International

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Purpose. To report one-year outcomes of a modified version of two-stage multimodal surgical protocol for moderate keratoconus which has been suggesting promising preliminary results. Materials and Methods. 30 eyes of 25 patients with moderate keratoconus who exhibited visual complaints and/or disease progression were included for this retrospective case study. Approximately 3 months after implantation of intracorneal ring segment (Intacs SK™), a combination of corneal wavefront-guided transepithelial photorefractive keratectomy (CWG-transPRK, Schwind Amaris® 1050, and Schwind Sirius) and accelerated collagen cross-linking (accCXL, Avedro KXL™) was performed. Patients were examined for uncorrected and corrected distance visual acuity (UDVA; CDVA), keratometric power (K), corneal thickness, and corneal higher-order aberrations (HOAs) preoperatively and at postoperative 1, 3, 6, and 12 months. Results. The median UDVA and mean CDVA were enhanced from 6/38 to 6/12 and from 6/19 to 6/7.5, respectively, through 12 months after CWG-transPRK/accCXL. The 12-month CDVA of all patients was better than 6/12 Snellen, and no subject lost one or more lines of CDVA. The magnitudes of both myopia and corneal steepness were decreased in turn by Intacs SK implantation and also by CWG-transPRK/accCXL, but the reduction in HOA was largely the result of CWG-transPRK/accCXL. The magnitude of corneal thinning stabilized within 3 months after CWG-transPRK/accCXL. Conclusion. This approach may allow patients with moderate keratoconus to obtain satisfactory vision without the need for contact lens wear. This surgery appeared to be effective and safe through 1 year of follow-up.

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Simultaneous Transepithelial Topography-Guided Photorefractive Keratectomy and Accelerated Cross-Linking in Keratoconus: 2-Year Follow-Up

Cited by 18 publications

References 24 publications

Visual improvement after corneal collagen cross-linking in keratoconus

Visual improvement after corneal collagen cross-linking in keratoconus

A cutting-edge refractive surgery treatment option for Forme Frust keratoconus

One-Year Efficacy and Safety of Combined Photorefractive Keratectomy and Accelerated Corneal Collagen Cross-Linking after Intacs SK Intracorneal Ring Segment Implantation in Moderate Keratoconus

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