Síndrome antisintetasa: análisis de 11 casos

Zamarrón, Ester; Carrera, Luis Gómez; Bonilla, Gema; Petit, D.; Mangas, Alberto; Álvarez-Sala, R.

doi:10.1016/j.medcli.2016.11.021

Cited by 8 publications

(3 citation statements)

References 11 publications

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“…En general los pacientes con Anti Jo-1 positivo tienen una evolución más favorable. 12,13 Si bien Targoff IN y colaboradores informaron sobre la presencia del Anti TIF-1γ en pacientes con DM y/o DMCA vinculados con neoplasia y disfagia (siendo esta última menos frecuente) 14,15 existen 4 tipos de Anti-TIF1 (Anti-TIF1γ Anti-TIF1β; Anti-TIF1α; Anti-TIF1δ). El Anti-TIF1γ se asocia con mayor frecuencia a malignidad, como cáncer de hígado, gástrico, pulmón, mama y próstata; y a disfagia.…”

Section: Discussionunclassified

Series of clinical cases of patients with idiopathic inflammatory myopathy and interstitial lung disease from the registry of idiopathic inflammatory myopathies of the Argentine Society of Rheumatology

Ponce

Zalazar

Coello

et al. 2020

Rev. Argent. Reumatol.

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Idiopathic Inflammatory Myopathies (MII) are a heterogeneous group of diseases characterized by muscle weakness and inflammation underlying muscle biopsy. The main organs affected are muscle, skin and the lung can also be affected. They are distinguished within clinical subtypes such as Polymyositis (PM), Dermatomyositis (DM), DM with the variant Clinically Amiopathic Dermatomyositis (DMCA), the Syndrome Antisynthetase (SAS), Immune-mediated Necrotizing Myositis, Body Myositis Inclusion (MCI) and Neoplasia-Associated Myositis. The presence of certain specific and associated antibodies predisposes to the development of clinical manifestations, determining the disease prognosis. 4 patients from the Registry of MII of the Argentine Society of Rheumatology (SAR) are presented with these characteristics: one patient with PM and anti Jo-1 positive and three patients with DM (one with DMCA and anti-RO 52 and two patients with anti-PL7 and anti-TI-F1γ respectively).

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Section: Discussionunclassified

Series of clinical cases of patients with idiopathic inflammatory myopathy and interstitial lung disease from the registry of idiopathic inflammatory myopathies of the Argentine Society of Rheumatology

Ponce

Zalazar

Coello

et al. 2020

Rev. Argent. Reumatol.

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“…El SAS afecta con mayor frecuencia el sexo femenino, con una relación mujer-varón 2:1 [4][5][6][7][8][9][10][11][12] . Generalmente se presenta durante la cuarta década de la vida, al igual que nuestro caso clínico.…”

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“…Coincidente con las manifestaciones clínicas de nuestra paciente, la tríada clásica de síntomas descritos en el SAS incluye: EPI, miositis y artritis. Sin embargo, solo una minoría de los pacientes (19% en un estudio) exhibe la tríada completa al inicio de la enfermedad 2,12,15 .…”

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Síndrome antisintetasa: reporte de un caso

Lobo

Sola

Giardullo

et al. 2022

Rev. Argent. Reumatol.

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El síndrome antisintetasa es una miopatía inflamatoria autoinmune poco frecuente que se caracteriza por la presencia de autoanticuerpos anti sintetasa ARNt (generalmente anti JO1) asociado frecuentemente a miositis, enfermedad pulmonar intersticial, poliartritis, manos de mecánico y fenómeno de Raynaud. Se reporta el caso de una mujer de 45 años que presenta este síndrome con características fenotípicas de dermatomiositis y responde de forma favorable luego de la administración de tratamiento con glucocorticoides asociado a metotrexato.

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Antisynthetase syndrome. Multidisciplinary evaluation and comittment

Selva-O’Callaghan

Trallero-Araguás

2017

Medicina Clínica (English Edition)

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Síndrome antisintetasa: análisis de 11 casos

Cited by 8 publications

References 11 publications

Series of clinical cases of patients with idiopathic inflammatory myopathy and interstitial lung disease from the registry of idiopathic inflammatory myopathies of the Argentine Society of Rheumatology

Series of clinical cases of patients with idiopathic inflammatory myopathy and interstitial lung disease from the registry of idiopathic inflammatory myopathies of the Argentine Society of Rheumatology

Síndrome antisintetasa: reporte de un caso

Antisynthetase syndrome. Multidisciplinary evaluation and comittment

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