Singapore Malay Eye Study: rationale and methodology of 6‐year follow‐up study (SiMES‐2)

Abstract

SiMES-2 will be one of the few follow-up epidemiological eye studies among Asians and will determine the cumulative 6-year incidence, progression, risk factors and impact of major eye diseases in Singaporean Malay adults.

Peripapillary choroidal thickness assessed using automated choroidal segmentation software in an Asian population

“…The subjects in this study were enrolled from the Singapore Malay Eye Study (SiMES), a population-based cohort study of eye diseases in the Malay population aged 40–80 years in Singapore 13. The baseline examination was conducted between 2004 and 2006 and a follow-up examination of the SiMES participants has been conducted since January 2011, 6 years after the baseline examination.…”

Retinal neurodegeneration on optical coherence tomography and cerebral atrophy

“…For this study, we focused on participants drawn from the first follow-up examination of the Singapore Malay Eye Study (SiMES-2) component of the SEED study who had OCT data available [23]. In order to use limited MRI imaging resources efficiently, it was decided to focus on subjects most likely to have cognitive problems.…”

Association of neuropsychiatric symptoms and sub-syndromes with cognitive impairment in community-dwelling Asian elderly

“…For this study, we focused on the Chinese (Hilal et al, 2013) and Malay components (Rosman et al, 2012) of the EDIS Study, as the recruitment of the Indians is ongoing. For this study, we focused on the Chinese (Hilal et al, 2013) and Malay components (Rosman et al, 2012) of the EDIS Study, as the recruitment of the Indians is ongoing.…”