Single and coinoculation of Serendipita herbamans with arbuscular mycorrhizal fungi reduces Fusarium wilt in tomato and slows disease progression in the long-term

Hallasgo, Anna Marie; Hauser, Constanze; Steinkellner, Siegrid; Hage‐Ahmed, Karin

doi:10.1016/j.biocontrol.2022.104876

Cited by 8 publications

(7 citation statements)

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“…Compared with literary works, we found that the pyrazole skeleton and its derivatives exhibited excellent inhibitory activity against Fusarium oxysporum [66]. Using the agar diffusion process, we determined the in vitro antifungal ability of 11 compounds (7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17) against the pathogenic fungus (F.o.a). The synthetic route of the target compounds (7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17) was carried out following Claisen condensation under mild conditions [24,26,[67][68][69][70][71][72][73][74].…”

Section: β-Keto-enol Derivatives a β-Keto-enol Pyridine And Furan Der...mentioning

confidence: 99%

“…Using the agar diffusion process, we determined the in vitro antifungal ability of 11 compounds (7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17) against the pathogenic fungus (F.o.a). The synthetic route of the target compounds (7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17) was carried out following Claisen condensation under mild conditions [24,26,[67][68][69][70][71][72][73][74]. Using the protocol described in the literature [27], the percentages of inhibition and semi-maximal inhibitory concentration (IC 50 ) were measured and estimated using the inhibition percentage non-linear regression equation, while benomyl was used as a positive control (Table 2).…”

Section: β-Keto-enol Derivatives a β-Keto-enol Pyridine And Furan Der...mentioning

confidence: 99%

“…As presented in Table 2, the fungal activity of 7 is very substantial, though it decreases slightly in the case of 10 because of ethoxy phenyl groups, which commonly have pharmacophore sites (δ − •••δ + ), as presented in Figure 1, due to their physicochemical properties and their ability to penetrate the envelope of fungal cells and enter their cellular place of action, thus displaying more excellent activity in [27]. Using the agar diffusion process, we determined the in vitro antifungal ability of 11 compounds (7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17) against the pathogenic fungus (F.o.a). The synthetic route of the target compounds (7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17) was carried out following Claisen condensation under mild conditions [24,26,[67][68][69][70][71][72][73][74].…”

Section: β-Keto-enolmentioning

confidence: 99%

“…Using the protocol described in the literature [27], the percentages of inhibition and semi-maximal inhibitory concentration (IC50) were measured and estimated using the inhibition percentage non-linear regression equation, while benomyl was used as a positive control (Table 2). Using the agar diffusion process, we determined the in vitro antifungal ability of 11 compounds (7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17) against the pathogenic fungus (F.o.a). The synthetic route of the target compounds (7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17) was carried out following Claisen condensation under mild conditions [24,26,[67][68][69][70][71][72][73][74].…”

Section: β-Keto-enolmentioning

confidence: 99%

“…Bayoud disease [1][2][3][4][5], caused by the telluric fungus pathogen Fusarium oxysporum f. sp. albedinis (F.o.a) [6][7][8][9], represents the leading dangerous agent of date palms cultivation, having killed more than 15 million Moroccan and Algerian date palm trees. Fungal infection causes significant implications, threatening date palms with high morbidity and mortality every year worldwide.…”

Section: Introductionmentioning

confidence: 99%

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An Insight into All Tested Small Molecules against Fusarium oxysporum f. sp. Albedinis: A Comparative Review

et al. 2022

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Bayoud disease affects date palms in North Africa and the Middle East, and many researchers have used various methods to fight it. One of those methods is the chemical use of synthetic compounds, which raises questions centred around the compounds and common features used to prepare targeted molecules. In this review, 100 compounds of tested small molecules, collected from 2002 to 2022 in Web of Sciences, were divided into ten different classes against the main cause of Bayoud disease pathogen Fusarium oxysporum f. sp. albedinis (F.o.a.) with structure–activity relationship (SAR) interpretations for pharmacophore site predictions as (δ−···δ−), where 12 compounds are the most efficient (one compound from each group). The compounds, i.e., (Z)-1-(1.5-Dimethyl-1H-pyrazole-3-yl)-3-hydroxy but-2-en-1-one 7, (Z)-3-(phenyl)-1-(1,5-dimethyl-1H-pyrazole-3-yl)-3-hydroxyprop-2-en-1-one 23, (Z)-1-(1,5-Dimethyl-1H-pyrazole-3-yl)-3-hydroxy-3-(pyridine-2-yl)prop-2-en-1-one 29, and 2,3-bis-[(2-hydroxy-2-phenyl)ethenyl]-6-nitro-quinoxaline 61, have antifungal pharmacophore sites (δ−···δ−) in common in N1---O4, whereas other compounds have only one δ− pharmacophore site pushed by the donor effect of the substituents on the phenyl rings. This specificity interferes in the biological activity against F.o.a. Further understanding of mechanistic drug–target interactions on this subject is currently underway.

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