Single-center, consecutive series study of the use of a novel platelet-rich fibrin matrix (PRFM) and beta-tricalcium phosphate in posterolateral lumbar fusion

Callanan, Tucker C.; Brecevich, Antonio T.; Steiner, Craig; Xavier, Fred; Iorio, Justin; Abjornson, Celeste; Cammisa, Frank P.

doi:10.1007/s00586-018-5832-5

Cited by 3 publications

(10 citation statements)

References 25 publications

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“…com/CJP/A846), while 32 (9.7%) reported that they tracked opioid use. However, of these 32, only 21 studies (6.4% of all studies) 41,[43][44][45][46][47]49,52,53,[56][57][58][60][61][62][63]65,[69][70][71][72] specifically reported opioid use out to at least 6 months (Table 2). Eleven of the 329 studies 42,48,50,51,54,55,59,64,[66][67][68] tracked opioid use before surgery or immediately after surgery but did not track opioids out at least 6 months.…”

Section: Characteristics Of Included Studiesmentioning

confidence: 99%

“…Cohen's kappa for agreement among the independent reviewers for the title and abstract screen was moderate (k = 0.79) and for the full-text screen was almost perfect (k = 0.95). Detailed descriptions of the 21 studies 41,[43][44][45][46][47]49,52,53,[56][57][58][60][61][62][63]65,[69][70][71][72] that tracked longterm opioid use are provided in Table 2. There were 2286 pooled participants across all studies with a mean age ranging from 39.2 to 71.0 years, with 53.6% (n = 1226) female.…”

Section: Characteristics Of Included Studiesmentioning

confidence: 99%

“…The number of participants in the fusion arm within each study ranged from 26 to 322. Of these studies, 12 were RCTs, 43,44,47,53,56,57,61,62,[69][70][71][72] 6 were prospective cohort studies, 45,46,52,58,60,63 and 3 were retrospective cohort studies. 41,49,65 The study follow-up period ranged from 7.2 to 72.0 months.…”

Section: Characteristics Of Included Studiesmentioning

confidence: 99%

“…Sixteen 41,[44][45][46][47]52,53,[56][57][58]61,62,65,[70][71][72] of the 21 studies 41,43-47,49,52,53,56-58,60-63,65,69-72 (76%) were published between 2011 and 2020. For studies that tracked opioid use up to 6 months postsurgery, 57% (n = 12) were RCTs, 43,44,47,53,56,57,61,62,[69][70][71][72] 29% (n = 6) were prospective cohort studies 45,46,52,58,60,63 and 14% (n = 3) were retrospective cohort studies. 41,49,65 Studies that tracked opioid use <6 months or not at all were similar in study design parameters.…”

Section: Study Design Parametersmentioning

confidence: 99%

“…In order to track opioid use both before and after surgery, 5 studies used patient self-report, 43,53,57,58,61 three studies used medical records review 41,49,65 and 13 studies did not report their method. [44][45][46][47]52,56,60,62,63,[69][70][71][72] Of the 3 studies that used medical records data, the exact methodology for assessing opioid use (prescriptions vs. other tracking) was unclear for 1 study. 49 The second study used prescriptions filled to calculate opioid use.…”

Section: Characteristics Of Long-term Opioid Usementioning

confidence: 99%

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More Than 1 in 3 Patients With Chronic Low Back Pain Continue to Use Opioids Long-term After Spinal Fusion

Vraa

Myers

Young

et al. 2021

The Clinical Journal of Pain

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Objective: A common expectation for patients after elective spine surgery is that the procedure will result in pain reduction and minimize the need for pain medication. Most studies report changes in pain and function after spine surgery, but few report the extent of opioid use after surgery. This systematic review aims to identify the rates of opioid use after lumbar spine fusion.Materials and Methods: PubMed, CINAHL, Cochrane Central Register of Controlled Trials, and Ovid Medline were searched to identify studies published between January 1, 2005 and June 30, 2020 that assessed the effectiveness of lumbar fusion for the management of low back pain.Results: Of 6872 abstracts initially identified, 329 studies met the final inclusion criteria, and only 32 (9.7%) reported any postoperative opioid use. Long-term opioid use after surgery persists for more than 1 in 3 patients with usage ranging from 6 to 85.9% and a pooled mean of 35.0% based on data from 21 studies (6.4% of all lumbar fusion studies).Discussion: Overall, opioid use is not reported in the majority of lumbar fusion trials. Patients may expect a reduced need for opioidbased pain management after surgery, but the limited data available suggests long-term use is common. Lack of consistent reporting of these outcomes limits definitive conclusions regarding the efficacy of spinal fusion for reducing long-term opioid. Patient decisions about undergoing surgery may be altered if they had realistic expectations about rates of postsurgical opioid use. Spine surgery trials should track opioid utilization out to a minimum of 6 months after surgery as a core outcome.

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Section: Characteristics Of Included Studiesmentioning

confidence: 99%

Section: Characteristics Of Included Studiesmentioning

confidence: 99%

Section: Characteristics Of Included Studiesmentioning

confidence: 99%

Section: Study Design Parametersmentioning

confidence: 99%

Section: Characteristics Of Long-term Opioid Usementioning

confidence: 99%

See 3 more Smart Citations

More Than 1 in 3 Patients With Chronic Low Back Pain Continue to Use Opioids Long-term After Spinal Fusion

Vraa

Myers

Young

et al. 2021

The Clinical Journal of Pain

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Is adjunction of advanced platelet-rich fibrin (A-PRF) useful in first metatarsophalangeal joint arthrodesis? A retrospective cohort study

et al. 2020

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To corset or not to corset after lumbar spine fixation surgery?: A prospective randomized clinical trial and literature review

Chen,

Yang,

Lin

et al. 2024

Medicine

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Purpose: Orthosis after lumbar fusion surgery is common. However, the evidence for benefit remains to be determined, especially in tropical areas with heavy workers. To investigate postoperative orthosis and whether it affects pain improvement, quality of life, and fusion rate. Method: From May 2021 to May 2022, this single-center prospective randomized clinical trial enrolled 110 patients. We excluded 9 patients, and 101 people were analyzed finally. Corset group, in which participants used a corset for 3 months postoperatively; Non-corset group, in which participants didn’t wear any orthosis. ODI and VAS scale were recorded before the surgery: 2 weeks, 1 month, 3 months, half a year, and 1 year postoperatively. The lumbar X-ray was done before the surgery, 6 months postoperatively. All complications in 1 year were recorded. Results: Significant decrease in VAS score in the non-corset group since post-operation day 5 (corset group 3.44 ± 1.77, non-corset group 3.36 ± 1.75, P = .0093) during admission, and also a decrease in admission duration (corset group 11.08 ± 2.39, non-corset group 9.55 ± 1.75, P = .0004) were found. There was a significantly better ODI score in the non-corset group since post-operation 1 month, while in the corset group until post-operation 3 months. Both groups had no significant difference in satisfaction, complication rates, and X-ray results, such as fusion, angular rotation, sagittal transition, and slip in the neutral position. Conclusion: After the transpedicular screw fixation with posterolateral fusion surgery for degenerative spondylolisthesis, non-orthosis is a safe strategy. It can reduce the admission duration and has the trend for better functional outcomes.

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Single-center, consecutive series study of the use of a novel platelet-rich fibrin matrix (PRFM) and beta-tricalcium phosphate in posterolateral lumbar fusion

Cited by 3 publications

References 25 publications

More Than 1 in 3 Patients With Chronic Low Back Pain Continue to Use Opioids Long-term After Spinal Fusion

More Than 1 in 3 Patients With Chronic Low Back Pain Continue to Use Opioids Long-term After Spinal Fusion

Is adjunction of advanced platelet-rich fibrin (A-PRF) useful in first metatarsophalangeal joint arthrodesis? A retrospective cohort study

To corset or not to corset after lumbar spine fixation surgery?: A prospective randomized clinical trial and literature review

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