Single‐fiber electromyography in amyotrophic lateral sclerosis and cervical spondylosis

Abstract

Single-fiber electromyography can supply valuable information in helping to differentiate ALS from CS.

Quantitating Changes in Jitter and Spike Number Using Concentric Needle Electrodes in Amyotrophic Lateral Sclerosis Patients

“…Although SFEMG has been suggested as one of the quantitative methods for supporting chronic partial denervation in ALS by the revised EI Escorial criteria,[ 9 ] few reports have studied SFEMG in neurogenic diseases. [ 1 10 11 12 13 ] We are interested in whether the CN-jitter and spike number can substitute the SFN-jitter and SFN-FD to assess neuromuscular junction transmission and chronic reinnervation in neurogenic diseases.…”

“…Recordings with both electrodes were performed on the extensor digitorum communis (EDC) muscle under voluntary contraction on the same day. [ 12 13 ] In ALS patients, the Medical Research Council scale was grade 5 in the EDC muscles studied. The SFN-jitter and single-fiber needle-fiber density (SFN-FD) were defined using SFNs and the SFEMG program.…”

“…SFEMG could also provide some information for evaluating the prognosis of ALS and differentiating ALS from cervical spondylosis. [ 10 11 12 13 ]…”

The contribution of neurophysiology in the diagnosis and management of cervical spondylotic myelopathy: a review

“…A single-fiber EMG study has been performed in 26 patients with ALS, 19 with ALS and CS and 22 with isolated CS. 9 Mean jitter, percentage of jitter 455 μs and percentage of impulse blocking were not statistically different between ALS patients with and without concomitant CS but were significantly lower in patients with isolated CS. Mean fiber density was not statistically different among the three patient groups.…”

A Convenient Non-harm Cervical Spondylosis Intelligent Identity method based on Machine Learning

“…A large number of auxiliary inspection methods are used to assist the identification. The following methods [11][12][13][14][15][16] included in the domestic and foreign objective examination of the CS are clinical examinations, spinal angiography, vertebral artery angiography, X-ray, computed tomography(CT), and magnetic resonance imaging(MRI), etc. Most of them depend on expensive medical instruments in hospital to directly observe the physical changes in the spine and ancillary structures.…”