Background: The use of single-incision plus one-port laparoscopic pancreaticoduodenectomy (SILPD+1) has been never reported and its safety and efficacy remain unknown. The objective of the study is to evaluate the short-term outcomes of SILPD+1 compared with conventional laparoscopic pancreaticoduodenectomy (CLPD).
Method: Fifty-seven cases of laparoscopic pancreaticoduodenectomy (LPD) were performed by a single surgical team in the Department of Pancreatic Surgery, West China Hospital, Sichuan University between November 2021, and March 2022. Among these, 10 cases of LPD were performed using a single-incision plus one-port device. Based on the same inclusion and exclusion criteria, 47 cases of LPD performed using traditional 5-trocar were included as a control group. The patient’s demographic characteristics, intraoperative, and postoperative variables were prospectively collected and retrospectively analyzed.
Results: Three men and seven women were included in the SILPD+1 group. All baseline parameters of both groups were comparable except for age. Patients were younger in the SILPD+1 group (47.2 ± 18.3 years vs 60.6 ± 11.7 years, P = 0.05) than that in the CLPD group. Compared to the CLPD group, median operation time (222.5 (208.8–245.0) vs. 305.0 (256.0-337.0) min, P < 0.001) was shorter, median postoperative VAS scores on days 1-3 were lower, and median cosmetic score (21.0 (19.0-23.5) vs. 17.0 (16.0-20.0), P = 0.026) was higher one month after the surgery in SILPD+1 group. The estimated blood loss, conversion rate, blood transfusion rate, exhaust time, time of drainage tube removal, postoperative hospital stays, and perioperative complications were comparable between the two groups.
Conclusion: In a high-volume LPD center, SILPD+1 is safe and feasible without increasing the operation time and complications. It even has the advantages of reduced postoperative pain and improved cosmetic results.