Single posterior debridement, interbody fusion, and fixation on patients with continuous multivertebral lumbar spine tuberculosis (CMLSTB)

Long, Weihong; Gong, Liqun; Cui, Yaqing; Qi, Jie; Duan, Dapeng; Li, Weiwei

doi:10.1186/s12891-020-03628-0

Cited by 3 publications

(3 citation statements)

References 26 publications

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“…The TPO always present over the surface of follicular cells of thyroid gland and destroy their structure to by activate cascade reaction so that, we can say IL-36 was inflammatory mediator which promote the progression of diseases in HT patients. 17 But Tg-Ab show non-significant correlation with IL-36 γ. The IL-36 γ show non-significant but positive correlation with FT3.…”

Section: Discussionmentioning

confidence: 91%

Clinical Significance of Elevated Serum IL-36γ Levels in Patients with Early-Stage Hashimoto’s Thyroiditis

Arif¹,

Sakhawat²,

Nawaz³

et al. 2023

PJMHS

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Background: Hypothyroidism was the diagnosed and treated as a result of health related quality of life issues. The aim of this study was that to evaluate the effect of IL-36 γ, Tg-Ab and TOP-Ab in the Hashimoto’s Thyroiditis (HT). Study design: This was a cross sectional study conducted at Rawal Institute of health sciences, Islamabad duration of study was six month, from April 2022 to September 2022. Methods: A total number of the patients was n=150 which divided into two group, control and HT group. To perform EISA for the estimation of free triiodothyronine 3, 4 (FT3, FT4), thyroid stimulating hormone (TSH), thyroid peroxidase antibody (TOP-Ab) and thyroid globulin antibody (Tg-Ab). The data was analyzed by SPSS 21. Results: The serum IL-36γ show correlation with the TOP-Ab and FT3 in HT. The IL-36γ was significantly higher in HT as compared to the control group; p<0.001**. The IL-36γ show significant negative correlation with TOP-Ab (<0.001**, r-0.126) and non- significant positive correlation with FT3 (0.321, r= + 0.28) in HT patients. The Tg-Ab was show non- significant correlation with IL-36 γ; (P<=0. 928, r = 0.323). Conclusions: IL-36 γ is diagnostic marker and show negative correlation with TPO-Ab in the patient serum of HT. Il-36 γ had significantly high in the HT patients. IL-36 γ may involve to the progression of pathogenesis and enhance the inflammatory responses. In HT, Tg-Ab was significantly reduced than TPO-Ab but both contribute to the production of thyroid hormones. Keywords: Interleukin, Thyroxin, Thyroid stimulating hormone, Peroxidase.

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Section: Discussionmentioning

confidence: 91%

Clinical Significance of Elevated Serum IL-36γ Levels in Patients with Early-Stage Hashimoto’s Thyroiditis

Arif¹,

Sakhawat²,

Nawaz³

et al. 2023

PJMHS

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“…Traditional anterior approach had once been the standard protocol due to excellent ability in debridement and reconstruction, whereas large incisions with unignorable vascular or visceral morbidities had raised increasing concerns. As an alternative, posterior-only approach was increasingly popularized with advantages in effective alignment reconstruction and instrumentation [ 4 , 5 ]. However, excessive soft tissue dissection with inconvenient surgical routine and obstructed visualization had prevented the technique from becoming an optimal protocol complying with minimal invasiveness principle.…”

Section: Introductionmentioning

confidence: 99%

“…As an alternative, posterior-only approach was increasingly popularized with advantages in effective alignment reconstruction and instrumentation. 4,5 However, excessive soft tissue dissection with inconvenient surgical routine and obstructed visualization had prevented the technique from becoming an optimal protocol complying with minimal invasiveness principle.…”

Section: Introductionmentioning

confidence: 99%

Simultaneous Single-Position Oblique Lateral Interbody Fusion Combined With Unilateral Percutaneous Pedicle Screw Fixation for Single-Level Lumbar Tuberculosis: A 3-Year Retrospective Comparative Study

He,

Deng,

Yang

et al. 2023

Neurospine

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Objective: To illustrate a simultaneous single-position oblique lateral interbody fusion (SPOLIF) combined with unilateral percutaneous pedicle screw fixation in treating single-level lumbar tuberculosis, compared with posterior-only approach in clinical and radiographic evaluations.Methods: Consecutive patients who had undergone surgeries for single-level lumbar tuberculosis from January 2018 to December 2020 were retrospectively reviewed. The patients included were divided into SP-OLIF and posterior-only groups according to surgical methods applied, with follow-up for at least 36 months. Outcomes included estimated blood loss, operative time, and complications for safety evaluation; visual analogue scale (VAS), Oswestry Disability Index (ODI) for efficacy evaluation; erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) for evaluating tuberculosis activity; x-ray and computed tomography scan were used for radiographic evaluation.Results: A total of 136 patients had been enrolled in the study (60 for SP-OLIF and 76 for Posterior-only). The median operative time, blood loss, and hospital stay in SP-OLIF group were significantly less, with a lower complication rate. Meanwhile, the SP-OLIF group showed substantially lower VAS in 1 and 7 days and decreased ODI in the first month postoperatively, without significant difference afterward. Similarly, the median CRP and ESR in SP-OLIF group were significantly lower in 3 and 7 days postoperatively. All indicators had reduced to normal after 3 months. No recurrence had been reported throughout the whole follow-up.Conclusion: SP-OLIF was an efficient minimally invasive protocol for single-level lumbar tuberculosis, facilitating earlier clinical improvement, with decreased blood loss, operative time and hospital stay compared with posterior-only approach.

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Multitrack and multianchor point screw technique combined with the Wiltse approach for lesion debridement for lumbar tuberculosis

Yuan¹,

Ren²,

Zhang³

et al. 2023

World J Clin Cases

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Single posterior debridement, interbody fusion, and fixation on patients with continuous multivertebral lumbar spine tuberculosis (CMLSTB)

Cited by 3 publications

References 26 publications

Clinical Significance of Elevated Serum IL-36γ Levels in Patients with Early-Stage Hashimoto’s Thyroiditis

Clinical Significance of Elevated Serum IL-36γ Levels in Patients with Early-Stage Hashimoto’s Thyroiditis

Simultaneous Single-Position Oblique Lateral Interbody Fusion Combined With Unilateral Percutaneous Pedicle Screw Fixation for Single-Level Lumbar Tuberculosis: A 3-Year Retrospective Comparative Study

Multitrack and multianchor point screw technique combined with the Wiltse approach for lesion debridement for lumbar tuberculosis

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