Single-Shot Turbo Spin-Echo Diffusion-Weighted Imaging for Retinoblastoma: Initial Experience

Graaf, Pim de; Pouwels, Petra J. W.; Rodjan, Firazia; Moll, Annette C.; Imhof, Saskia M.; Knol, Dirk L.; Sánchez, Esther; Valk, Paul van der; Castelijns, Jonas A.

doi:10.3174/ajnr.a2729

Cited by 57 publications

(38 citation statements)

References 23 publications

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“…[7][8][9][10][11] Previous reports showed variable DWI intensities and ADCs in retinoblastomas, depending on their histology and cellularity. 3 Abdel Razek et al 4 reported that the mean ADC was 0.49 6 0.12 3 10 23 mm 2 s 21 on EP imaging, which is lower than the mean ADC of the present study. They mentioned that the ADC values were significantly lower in their patients with optic nerve invasion.…”

Section: Discussioncontrasting

confidence: 55%

“…2,5 Diffusion-weighted imaging (DWI) is widely used to diagnose tumours, inflammation and vascular disease in both intracranial and extracranial lesions. 3,4,[6][7][8][9][10][11][12][13][14][15][16] Previous studies also revealed the efficacy of DWI to evaluate orbital lesions including orbital tumours of adults 8,9 and children, 10 ocular adnexal lymphomas, 9,11 immunoglobulin G4 (IgG4)-related disease, 9 endophthalmitis 12 and optic nerve lesions. 13,14 However, it is sometimes difficult to evaluate intraorbital structures with echoplanar (EP) imaging, which is the most common imaging technique for DWI.…”

Section: Introductionmentioning

confidence: 99%

“…[1][2][3][4][5] Diagnoses of retinoblastoma are usually made by fundoscopy and ultrasound. 1,2 However, MRI is recommended to evaluate extraocular extension and the presence of intracranial lesions.…”

Section: Introductionmentioning

confidence: 99%

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3D turbo field echo with diffusion-sensitized driven-equilibrium preparation technique (DSDE-TFE) versus echo planar imaging in evaluation of diffusivity of retinoblastoma

Hiwatashi¹,

Togao²,

Yamashita³

et al. 2016

BJR

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Makoto Obara is an employee of Philips Electronics Japan. He was not involved in data analysis in this study.Objective: Compared with echoplanar (EP) diffusionweighted imaging (DWI), three-dimensional (3D) turbo field echo with diffusion-sensitized driven-equilibrium (DSDE-TFE) preparation DWI obtains images with higher spatial resolution and less susceptibility artefacts. The purpose of this study was to evaluate the feasibility of DSDE-TFE to visualize retinoblastomas compared with EP imaging. Methods: This retrospective study was approved by our institutional review boards. Eight patients with retinoblastomas (five males and three females; age range 0-87 months; median 21 months) were studied. For the DSDE-TFE, motion-probing gradients (MPGs) were conducted at one direction with b-values of 0 and 500 s mm 22 and a voxel size of 1.5 3 1.5 3 1.5 mm 3 . For the EP imaging, MPGs were conducted at three directions with b-values of 0 and 1000 s mm 22 and a voxel size of 1.4 3 1.8 3 3 mm 3 . The apparent diffusion coefficients (ADCs) of each lesion were measured. Statistical analyses were performed with Pearson R and linear correlation coefficients. Results: Intraocular lesions were clearly visualized on the DSDE-TFE without obvious geometrical distortion, whereas all showed deformity on EP images. On the DSDE-TFE, the ADCs of the lesions ranged from 0.83 3 10 23 to 2.93 3 10 23 mm 2 s 21 (mean 6 standard deviation 1.73 6 0.73 3 10 23 mm 2 s 21 ). On the EP images, the ADCs ranged from 0.53 3 10 23 to 2.03 3 10 23 mm 2 s 21 (0.93 6 0.53 3 10 23 mm 2 s 21 ). There was a significant correlation in ADC measurement between the DSDE-TFE and EP imaging (r 5 0.81, p , 0.05). Conclusion: With its insensitivity to field inhomogeneity and high spatial resolution, the 3D DSDE-TFE technique enabled us to assess diffusivity in retinoblastomas. Advances in knowledge: DSDE-TFE could enable us to assess the ADC of retinoblastomas without obvious geometrical distortion.

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Section: Discussioncontrasting

confidence: 55%

Section: Introductionmentioning

confidence: 99%

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3D turbo field echo with diffusion-sensitized driven-equilibrium preparation technique (DSDE-TFE) versus echo planar imaging in evaluation of diffusivity of retinoblastoma

Hiwatashi¹,

Togao²,

Yamashita³

et al. 2016

BJR

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“…For example, single-shot turbo spin-echo diffusionweighted imaging could be used when susceptibility artifacts are too strong for EPI-DWI. 26 In addition, view angle tilting could be used with EPI to reduce geometric distortions caused by B 0 inhomogeneity. 27 This work was motivated by the possibility of correcting MRI artifacts induced by orthodontic appliances using permanent magnets with a strong coercivity (Rollins NK, presentation at Philips Pediatric MRI users meeting, January T VIII.…”

Section: Discussionmentioning

confidence: 99%

Induced magnetic moment in stainless steel components of orthodontic appliances in 1.5 T MRI scanners

et al. 2015

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Purpose: Most orthodontic appliances are made of stainless steel materials and induce severe magnetic susceptibility artifacts in brain MRI. In an effort for correcting these artifacts, it is important to know the value of induced magnetic moments in all parts of orthodontic appliances. In this study, the induced magnetic moment of stainless steel orthodontic brackets, molar bands, and arch-wires from several vendors is measured. Methods: Individual stainless steel brackets, molar bands, and short segments of arch-wire were positioned in the center of spherical flask filled with water through a thin plastic rod. The induced magnetic moment at 1.5 T was determined by fitting the B 0 map to the z-component of the magnetic dipole field using a computer routine.

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“…Ocular MRI holds the potential to provide guidance during diagnostic assessment and treatment of ophthalmological diseases [8,[10][11][12][13]. With a sensitivity that is close to that of CT, MRI can serve as a diagnostic tool for eye tumors as well as optic neuropathies such as optic neuritis [14][15][16][17][18][19][20]. Ultimately, the development of ocular MRI applications is aiming at MR image based biometry [21,22] to support advanced intraocular lens implantation or refilling procedures that restore visual function and accommodation [23].…”

Section: Introductionmentioning

confidence: 99%

Ophthalmic Magnetic Resonance Imaging at 7 T Using a 6-Channel Transceiver Radiofrequency Coil Array in Healthy Subjects and Patients With Intraocular Masses

Graessl¹,

Muhle²,

Schwerter³

et al. 2014

Investigative Radiology

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ObjectivesThis study is designed to examine the feasibility of ophthalmic MRI at 7.0 T using a local six-channel transmit/receive radiofrequency (RF) coil array in healthy volunteers and patients with intraocular masses. Materials and MethodsA novel six-element transceiver RF coil array that makes uses of loop elements and that is customized for eye imaging at 7.0 T is proposed. Considerations influencing the RF coil design and the characteristics of the proposed RF coil array are presented. Numerical electro-magnetic field (EMF) simulations were conducted to enhance the RF coil characteristics. Specific absorption rate (SAR) simulations and a thorough assessment of RF power deposition were performed to meet the safety requirements. Phantom experiments were carried out to validate the EMF simulations and to assess the real performance of the proposed transceiver array. Certified approval for clinical studies was provided by a local notified body prior to the in vivo studies. The suitability of the RF coil to image the human eye, optical nerve and orbit was examined in an in vivo feasibility study including (i) 3D gradient echo imaging (3D GRE), (ii) inversion recovery 3D gradient echo (3D IR-GRE) and (iii) 2D T2 weighted fast spin-echo (2D FSE) imaging. For this purpose healthy adult volunteers (n=17, mean age 3411 years) and patients with intraocular masses (uveal melanoma, n=5, mean age 576years) were investigated. ResultsAll subjects tolerated all examinations well with no relevant adverse events. The sixchannel coil array supports high resolution 3D GRE imaging with a spatial resolution as good as (0.2 x 0.2 x 1.0) mm 3 which facilitates the depiction of anatomical details of the eye. Rather uniform signal intensity across the eye was found. A mean signal-to-noise ratio (SNR) of approximately 35 was found for the lens while the vitreous humor showed an SNR of page 3 approximately 30. The lens-vitreous humor contrast-to-noise ratio was 8, which allows good differentiation between the lens and the vitreous compartment. Inversion recovery prepared 3D GRE using a spatial resolution of (0.4 x 0.4 x 1.0 mm) 3 was found to be feasible. T2-weighted 2D FSE imaging with the proposed RF coil afforded a spatial resolution of (0.25 x 0.25 x 0.7 mm) 3 . ConclusionsThis work provides valuable information on the feasibility of ophthalmic MRI at 7.0 T using a dedicated six-channel transceiver coil array that supports the acquisition of high contrast, high spatial resolution images in healthy volunteers and patients with intraocular masses. The results underscore the challenges of ocular imaging at 7.0 T and demonstrate that these issues can be offset by using tailored RF coil hardware. The benefits of such improvements would be in positive alignment with explorations that are designed to examine the potential of MRI for the assessment of spatial arrangements of the eye segments and their masses with the ultimate goal to provide imaging means for guiding treatment decisions in ophthalmological diseases.

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Single-Shot Turbo Spin-Echo Diffusion-Weighted Imaging for Retinoblastoma: Initial Experience

Cited by 57 publications

References 23 publications

3D turbo field echo with diffusion-sensitized driven-equilibrium preparation technique (DSDE-TFE) versus echo planar imaging in evaluation of diffusivity of retinoblastoma

3D turbo field echo with diffusion-sensitized driven-equilibrium preparation technique (DSDE-TFE) versus echo planar imaging in evaluation of diffusivity of retinoblastoma

Induced magnetic moment in stainless steel components of orthodontic appliances in 1.5 T MRI scanners

Ophthalmic Magnetic Resonance Imaging at 7 T Using a 6-Channel Transceiver Radiofrequency Coil Array in Healthy Subjects and Patients With Intraocular Masses

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