Single treatment of low-risk basal cell carcinomas with pulsed dye laser-mediated photodynamic therapy (PDL-PDT) compared with photodynamic therapy (PDT): A controlled, investigator-blinded, intra-individual prospective study

Photodynamic and photobiological effects of light-emitting diode (LED) therapy in dermatological disease: an update

“…Another randomized study showed the efficacy of narrowband red LED source coupled to BF-200 nano-emulsion [ 113 ]. Recent studies compared red light LED-PDT to daylight-PDT [ 114 , 115 ]. Both studies demonstrated slightly higher clearance and recurrence rates with LED therapy.…”

Adverse effects of topical photodynamic therapy: a consensus review and approach to management

“…Čarija et al . undertook a within‐patient, prospective, controlled study of LED PDT with pulse‐dye laser PDT in 15 patients with 62 BCC lesions . While there were similar pain scores between the treatment arms, lower clearance rates were seen at 12 months with pulse dye laser PDT.…”

Photodynamic Therapy for Non-Melanoma Skin Cancers

“…In addition, noncoherent light has shown moderate penetration depths of up to 5 mm for 630 nm light, and up to 1–2 cm for 700–800 nm light [28,29,30]. Results from studies using PDL–PDT on superficial and nodular BCC and Bowen’s disease have been mixed [22,31,32]. Coupled with the disadvantages of PDL-PDT as stated above, it is no surprise that most practitioners opt to perform LED–PDT given its convenience and similar efficacy.…”

“…1 patient did not respond to either treatment [32]. Another study with 15 patients, using an intra-individual split design, with 630 nm LED-PDT and 585 nm PDL-PDT on similarly sized BCCs (nodular or superficial), showed similar clearance rates with both treatments, but higher recurrence rates with PDL-PDT [31]. …”