Here we study a new kind of linear integral equations for a relativistic quantummechanical two-particle wave function ψ(x 1 , x 2 ), where x 1 , x 2 are spacetime points. In the case of retarded interaction, these integral equations are of Volterra-type in the in the time variables, i.e., they involve a time integration from 0 to t i = x 0 i , i = 1, 2. They are interesting not only in view of their applications in physics, but also because of the following mathematical features: (a) time and space variables are more interrelated than in normal time-dependent problems, (b) the integral kernels are singular, and the structure of these singularities is non-trivial, (c) they feature time delay. We formulate a number of examples of such equations for scalar wave functions and prove existence and uniqueness of solutions for them. We also point out open mathematical problems.