Sintered Fiber Metal Composites as a Basis for Attachment of Implants to Bone

Galante, Jorge O.; Rostoker, W.; Lueck, R.; Ray, Robert D.

doi:10.2106/00004623-197153010-00009

Cited by 411 publications

(131 citation statements)

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“…These results in human cancellous bone conflict with previous qualitative investigations which reported bone ingrowth within 4-12 weeks (Galante et al 1971, Bobyn et al 1980, Harris et al 1983, Harris and Jasty 1985. One of the reasons for the differences between our findings and others was that animal models were used.…”

Section: Discussioncontrasting

confidence: 86%

Progression of human bone ingrowth into porous-coated implants: Rate of bone ingrowth in humans

Hofmann

Bloebaum

Bachus

1997

Acta Orthopaedica Scandinavica

106

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Section: Discussioncontrasting

confidence: 86%

Progression of human bone ingrowth into porous-coated implants: Rate of bone ingrowth in humans

Hofmann

Bloebaum

Bachus

1997

Acta Orthopaedica Scandinavica

106

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“…Enhancement of the interface between the implants and cells has been attempted by creating open pores on the implant surface [38], making fiber metal composites [39], and treating the surface of the implants with calcium phosphates [40][41] by varying thermal conditions [42]. The interface was evaluated by cell adhesion, proliferation, and differentiation [35,43], as well as by cell morphology and cytoskeleton by scanning or confocal microscopy by synthesis of the proteins of the extracellular matrix and proteoglycans [36].…”

Section: Discussionmentioning

confidence: 99%

Porous composite prosthetic pylon for integration with skin and bone

Pitkin¹,

Raykhtsaum²,

Pilling³

et al. 2007

JRRD

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Abstract-This article presents results of the further development and testing of the "skin and bone integrated pylon" (SBIP-1) for percutaneous (through skin) connection of the residual bone with an external limb prosthesis. We investigated a composite structure (called the SBIP-2) made of titanium particles and fine wires using mathematical modeling and mechanical testing. Results showed that the strength of the pylon was comparable with that of anatomical bone. In vitro and in vivo animal studies on 30 rats showed that the reinforcement of the composite pylon did not compromise its previously shown capacity for inviting skin and bone cell ingrowth through the device. These findings provide evidence for the safe and reliable long-term percutaneous transfer of vital and therapeutic substances, signals, and necessary forces and moments from a prosthetic device to the body.

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“…Press-fit techniques provide optimal conditions for bone ingrowth and fixation. Pore size, boneimplant apposition, and material properties all influence bone ingrowth and long-term stability [4,15].…”

Section: Introductionmentioning

confidence: 99%

Survivorship of Monoblock Trabecular Metal Cups in Primary THA

Malizos

Bargiotas

Papatheodorou

et al. 2008

Clinical Orthopaedics &Amp; Related Research

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Monoblock trabecular metal cups are made of a novel porous material intended to enhance ingrowth and improve fixation. We prospectively followed 223 consecutive patients with 245 trabecular metal acetabular cups implanted during primary total hip arthroplasties to determine the overall survivorship of the implant, and any association of survivorship to primary diagnosis and age, and to determine the fate of polar gaps and cysts. Minimum followup was 36 months (mean, 60 months; range, 36-112 months). Patients were assessed with the Harris Hip score and the Oxford questionnaire and radiographically with standardized serial radiographs. At last followup, all cups were radiographically stable with no evidence of migration or progressive radiolucencies. The survivorship with reoperation as the end point was estimated at 98.75% with a 95% confidence interval. Three reoperations occurred during the first 36 months. The Harris hip score increased from 48 to 94 and the Oxford score was 16.4 at the last examination. We observed no difference in terms of survivorship among patients with osteoarthritis, osteonecrosis, or hip dysplasia. Seven of 14 (50%) osteoarthritis cysts and 10 of 33 (33.3%) polar gaps detected on postoperative radiographs decreased or filled, whereas none of the remainder deteriorated with time. Our midterm results suggest this implant may enhance fixation, but long-term followup is needed to confirm our findings.

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Sintered Fiber Metal Composites as a Basis for Attachment of Implants to Bone

Cited by 411 publications

References 0 publications

Progression of human bone ingrowth into porous-coated implants: Rate of bone ingrowth in humans

Progression of human bone ingrowth into porous-coated implants: Rate of bone ingrowth in humans

Porous composite prosthetic pylon for integration with skin and bone

Survivorship of Monoblock Trabecular Metal Cups in Primary THA

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