Sinupret® as add-on therapy to saline irrigation for children with acute Post-Viral Rhinosinusitis

Abstract

Background: The present randomized controlled study investigated the efficacy of the complex herbal medicine Sinupret® syrup in the treatment of acute post-viral rhinosinusitis in children. Methods: The patients were children aged from 6 to 11 years (mean 9.4 years old). They were randomized into two groups. Both groups received a standard treatment including a symptomatic therapy and a saline therapy. Isotonic sea salt solution was given four times daily for a period of 14 days. The treatment group received an additional treatment with Sinupret® syrup 3-times daily. Using a 5-point scale (0-4 points), the physician evaluated the following symptomatic parameters at four successive visits (days 0, 5, 10 and 14): nasal congestion, nasal discharge, post-nasal drip and headache. Presence of cough in each group was recorded separately. Also using a 5-point scale (0-4 points), each patient gave a daily selfassessment of the following parameters from day 1 to day 10: rhinorrhea, headache, facial pain. Results: Relative to symptomatic therapy + saline irrigation, significant improvements were found in seven of the eightsymptomatic parameters under complex treatment including Sinupret® syrup. The differences in facial pain and the incidence of cough in groups were not significant. The need for prescription of antibiotics in the treatment group was 28.5% less than in the control group. No adverse reactions to the herbal medicine occurred during the study period. Conclusion: The complex herbal medicine Sinupret® syrup alleviates effectively the symptoms of acute post-viral rhinosinusitis in children. Furthermore, the prescription of antibiotics was also reduced.

Results of a randomised controlled study on the efficacy of a combination of saline irrigation and Sinupret syrup phytopreparation in the treatment of acute viral rhinosinusitis in children aged 6 to 11 years

“…Until now there has been limited knowledge of the beneficial effects of herbal medicines in the treatment of ARS in children. In our previous study, we investigated the effectiveness of Sinupret® in children with acute postviral RS with a positive effect [13]. Our current study result shows that administration of the herbal drug Sinupret® syrup (3.5 ml / 3 times daily) is effective in the treatment of acute viral rhinosinusitis in children aged 6 to 11.…”

Применение Фитотерапии Для Лечения Острого Риносинусита У Больных Поллинозом

“…Применение фитопрепаратов для лечения ОРС хорошо изучено [6,7] и эффективность их имеет подтверждение многолетней практикой [8,9]. Среди всех фитопрепаратов, при меняемых для лечения ОРС, особое место занимает Синупрет [10].…”