Sinusitis in immunodeficient and immunosuppressed patients

Berlinger, Norman T.

doi:10.1288/00005537-198501000-00009

Cited by 90 publications

(86 citation statements)

References 3 publications

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“…This is in agreement with Berlinger who reported poorly controlled diabetes to be one of the important risk factors. [12] Bodey GP also found similar finding from his study. [4] Wet blotting paper-like debris was found in more than half of the ear cases in the current study.…”

Section: Discussionsupporting

confidence: 76%

Fungal Infections in Ear, Nose and Throat: A Clinical Study

Karam¹,

Victor²,

Singh³

2018

AIMDR

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Background: Since the beginning of medical mycology at the turn of the century there has been a continual increase in the discovery of pathogenic fungi. The morbidity and mortality associated with these infections are becoming substantial and is emerging as a public health problem. Determining the rate of infections and determining the emerging pathogen and its potential risk factors will have an important influence on the prevention and control of these fungal diseases. Data regarding these is almost non-existent for the north-eastern part of the country. Aim: The present study was done to study the pattern of fungal infections in the north-eastern India in terms of clinical parameters and required diagnostic techniques. Methods: An observational cross-sectional study was done in which all the patients who attended the Otorhinolaryngology Department of Jawaharlal Nehru Institute of Medical Sciences,Imphal during the period of August 2015 to July 2017 with features suggestive of fungal infections were included. The exclusion criteria consisted of patients suffering from malignancies and receiving radiotherapy or chemotherapy. A detailed history was taken by using a structured, open interview schedule which had sections on socio-demography and case-history. Then, all the patients were given a thorough clinical examination followed by routine laboratory investigations, radiological examination and endoscopic examination wherever indicated. Further, the study subjects underwent mycological investigations. Data collected were analysed and presented descriptively.

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Section: Discussionsupporting

confidence: 76%

Fungal Infections in Ear, Nose and Throat: A Clinical Study

Karam¹,

Victor²,

Singh³

2018

AIMDR

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“…The occurrence of chronic graft versus host disease (cGVHD) is estimated to be of 60% in the patients submitted to allogenic transplants 1,2,4 . In this paper, the frequence found was low (30.5%).…”

Section: Discussionmentioning

confidence: 99%

“…Despite enhancements in the techniques and drugs used in current transplants, the bone marrow transplanted patient is prone to multiple upper airway infections and their complications during the first two years after the transplant 2,3 . Immunesupression, radiotherapy, chemotherapy, antibiotic therapy, graft versus host disease (GVHD) and viral infections are described as predisposing factors for these infections and complications [2][3][4][5] , although the exact predictive value is yet to be defined.…”

Section: Introductionmentioning

confidence: 99%

DECH crônica: fator preditivo para rinossinusite no transplante de medula óssea

Ortiz¹,

Sakano

Souza

et al. 2006

Rev. Bras. Otorrinolaringol.

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INTRODUÇÃO: transplante de medula óssea (TMO) é uma opção de tratamento para doenças hematológicas, tumorais e imunodeficiências e tem sido realizado com maior freqüência. O TMO predispõe a infecções de VAS e complicações, dentre estas as rinossinusites (RS). Quimioterapia, radioterapia, infecções virais, antibioticoterapia e doença do enxerto versus hospedeiro (DECH) são fatores predisponentes para RS. OBJETIVO: Verificar freqüência das RS no TMO e relação com DECH. Tentar estabelecer qual melhor tratamento para as RS no TMO. MÉTODO: Avaliação otorrinolaringológica de 2 grupos com 35 (gI) e 24 (gII) pacientes, antes e depois do TMO; e tratados individualmente com antibióticos e/ou punção de seios maxilares e/ou sinusectomia endoscópica. RESULTADOS: Nenhum apresentou RS antes do TMO; 42,8% dos TMO do gI tiveram RS e 34%, DECH; enquanto 58% do gII tiveram RS e 25%, DECH. No total, 49% tiveram RS e 30,5% com DECH. Houve significativa maior freqüência de RS em DECH crônica. A cirurgia foi indicada para tratamento de RS no TMO com DECH crônica. CONCLUSÃO: A freqüência de RS no TMO foi de 49%; DECH crônica é um fator predisponente para RS; a sinusectomia pode ser necessária nos pacientes com DECHc e RS.

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“…[2][3][4][5][6][7] The published estimated rate of rhinosinusitis in transplant patients is 36.9%. 3 The rate found in our study (32.2%) was roughly close to this estimate.…”

Section: Discussionmentioning

confidence: 99%

“…[2][3][4][5][6][7] Other complicating factors for respiratory infection are prolonged hospital stay, graft versus host disease, and corticosteroid therapy. [2][3][4][5][6][7] These patients have a 37% risk for developing rhinosinusitis after transplantation, compared to a 15% rate in patients with normal immune status. 3,8 Several laboratory tests are required by the hematology unit before HSCT, including paranasal sinus radiography, done in all patients to investigate possible sinus disease.…”

Section: Introductionmentioning

confidence: 99%

Valor prognóstico da tomografia computadorizada de seios paranasais no transplante de células-tronco hematopoiéticas

Ortiz¹,

Nakamura²,

Magalhães³

et al. 2010

Braz. j. otorhinolaryngol. (Impr.)

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sinusitis. CT scans are complementary exams used in the diagnosis of sinusitis; however, its use in every patient is questionable.Aim: to check the usefulness of ordering a CT scan prior to HSCT and to study the relationship between anatomical variations and sinusitis.Method: prospective study in which we performed paranasal CT scans before and after HSCT, using the Lund and Mackay score.Results: 77.5% and 61% of CT scans showed no evidence of sinus disease before and after HSCT. CT staging was not associated with sinusitis after HSCT. Anatomical variations were related to radiographic disease severity, but not to development of sinusitis after HSCT. There was no relation between pre-CT staging and sinusitis after BMT. Conclusion:CT scans are not useful for all patients before HSCT. Anatomical variation is not a predictive feature to sinusitis but it can determine its severity. Braz J Otorhinolaryngol. 2010;76(5):618-22. BJORL ORIGINAL ARTICLE

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Sinusitis in immunodeficient and immunosuppressed patients

Cited by 90 publications

References 3 publications

Fungal Infections in Ear, Nose and Throat: A Clinical Study

Fungal Infections in Ear, Nose and Throat: A Clinical Study

DECH crônica: fator preditivo para rinossinusite no transplante de medula óssea

Valor prognóstico da tomografia computadorizada de seios paranasais no transplante de células-tronco hematopoiéticas

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