Sitting–rising test: Sex- and age-reference scores derived from 6141 adults

Araújo, Cláudio Gil Soares de; Castro, Claudia Lúcia Barros de; Franca, João Felipe; Araújo, Denise Sms

doi:10.1177/2047487319847004

Cited by 19 publications

(18 citation statements)

References 7 publications

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“…However, because of the lack of temporality in the study design, the findings were prone to reverse causation bias. Furthermore, our findings were unexpected given the close inter-relationship between atherosclerotic CVD, VTE and physical fitness and also the fact that handgrip strength is a measure of whole-body muscle strength, correlated with leg strength, provides a valid index of overall limb muscle strength, and characterizes physical capability [26].…”

Section: Summary Of Main Findingsmentioning

confidence: 62%

Handgrip strength is not associated with risk of venous thromboembolism: a prospective cohort study

Kunutsor

Mäkikallio

Voutilainen

et al. 2020

Scandinavian Cardiovascular Journal

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Objectives. Consistent evidence suggests an inverse and independent association between handgrip strength and arterial thrombotic disease. However, whether handgrip strength is related to future risk of venous thromboembolism (VTE) is uncertain. We sought to assess the prospective association between handgrip strength and VTE risk. Design. Handgrip strength was assessed using a hand dynamometer in a population-based sample of 864 men and women aged 61-74 years without a history of VTE at baseline in the Kuopio Ischemic Heart Disease prospective cohort study. Handgrip strength was allometrically scaled to account for the effect of body weight (handgrip strength/body weight 2/3 ) and to normalize the data. Hazard ratios (HRs) with 95% confidence intervals (CIs) were estimated for VTE. Results. During a median (interquartile range) follow-up of 17.2 (12.1-18.3) years, 58 VTE events were recorded. The risk of VTE did not significantly decrease per 1 standard deviation increase in normalized handgrip strength in age-and sex-adjusted analysis (HR 0.89; 95% CI 0.65-1.22). The association remained similar in analyses adjusted for several established and emerging risk factors (HR 0.90; 95% CI 0.65-1.25).

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Section: Summary Of Main Findingsmentioning

confidence: 62%

Handgrip strength is not associated with risk of venous thromboembolism: a prospective cohort study

Kunutsor

Mäkikallio

Voutilainen

et al. 2020

Scandinavian Cardiovascular Journal

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“…Structured resistance training promotes muscle function and alleviate the levels of cardiometabolic risk factors [46]. There is growing evidence that objective measures of physical performance such as HS, sittingrising and standing balance tests not only characterize physical capability but also act as markers of general health status [47]. Handgrip strength decrease is also an indicator of frailty and age-associated loss of muscle mass [17] which appears to be inevitable and is likely to be the most significant contributing factor to the decline in muscle strength.…”

Section: Discussionmentioning

confidence: 99%

Handgrip strength is inversely associated with fatal cardiovascular and all-cause mortality events

et al. 2020

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Purpose: We aimed to assess the associations of handgrip strength (HS) with cardiovascular and all-cause mortality and whether adding data on HS to cardiovascular disease (CVD) risk factors is associated with improvement in CVD mortality prediction. Design: Handgrip strength was assessed in a population-based sample of 861 participants aged 61-74 years at baseline. Relative HS was obtained by dividing the absolute value by body weight. Results: During a median (interquartile range) follow-up of 17.3 (12.6-18.4) years, 116 fatal coronary heart diseases (CHDs), 195 fatal CVDs and 412 all-cause mortality events occurred. On adjustment for several risk factors, the hazard ratios (95% confidence intervals (CIs)) for fatal CHD, fatal CVD and all-cause mortality were 0.59 (0.37-0.95), 0.59 (0.41-0.86) and 0.66 (0.51-0.84), respectively, comparing extreme tertiles of relative HS. Adding relative HS to a CVD mortality risk prediction model containing established risk factors did not improve discrimination or reclassification using Harrell's C-index (C-index change: 0.0034; p ¼ .65), integrated-discrimination-improvement (0.0059; p ¼ .20) and net-reclassification-improvement (-1.31%; p ¼ .74); however, there was a significant difference in -2 log likelihood (p < .001). Conclusions: Relative HS is inversely associated with CHD, CVD and all-cause mortality events. Adding relative HS to conventional risk factors improves CVD risk assessment using sensitive measures of discrimination. KEY MESSAGESHandgrip strength (HS) assessment is simple, inexpensive and it takes only a few minutes to measure in clinical practice; however, its prognostic role for fatal cardiovascular outcomes on top of traditional risk factors in apparently healthy populations is uncertain. In a population-based prospective cohort study, good HS adjusted for body weight was associated with lower risk of fatal cardiovascular outcomes and the associations remained consistent across several clinically relevant subgroups. Handgrip strength may be a useful prognostic tool for fatal CHD and CVD events, in the general population.

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“…Based on their current study by Fonseca et al, 5 we can speculate that if they have used other assessment methods, like the 4-second exercise test, 6,7 - a very specific one for assessing cardiac vagal activity - and handgrip strength relative to body weight or maximal muscle power 8 or even a simple functional test like the sitting-rising test, 9 all of them, more specific to assess dynapenia, a likely clinically more relevant issue than sarcopenia, 10,11 they could have found additional discriminative values.…”

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confidence: 80%