Size Dependence of Particulate Calcium Phosphate Fillers in Dental Resin Composites

Abstract

Resin composites that consist of polymeric resins and functional fillers are commonly used as restorative materials for dental caries. Various types of calcium phosphates (CaPs) are studied as remineralizing fillers in the formulation of dental resin composites, which are generally inhibitory to demineralization of teeth, but the performance of resin composites has not yet been investigated comprehensively with respect to the size of CaP particles. In this study, the same tricalcium phosphate (TCP) particles within two different size ranges, the as-received TCP particles (TCP) and those resulted from grinding (TCP-G), were tested to determine the size dependence of CaP fillers in dental resin composites. The buffering capability, mechanical properties, ion release, antibacterial performance, and remineralization effect of TCP/TCP-G-containing composites were experimentally characterized and compared against two other commercial dental materials. The integration of micrometer-sized TCP particles resulted in a similar buffering effect and Ca 2+ /PO 4 3– release behaviors compared to the resin composite containing much smaller TCP-G particles. The flexural strength of the TCP-G resin composite was lower than that of the TCP composite after immersion in water for 30 days. However, the TCP-G composite facilitated crystal deposition toward better gap-closing performance at the dentin–composite interface. This study explored detailed insights about the size effect of CaP fillers, which is useful for the development of functional dental resin composites and their clinical translation.

Evaluation of Antibacterial Activity of a Bioactive Restorative Material Versus a Glass-Ionomer Cement on Streptococcus Mutans: In-Vitro Study

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Composite Containing Calcium Phosphate Particles Functionalized with 10-MDP

“…Experimental composites containing calcium orthophosphate particles were shown to promote enamel and dentin remineralization in vitro (Dickens and Flaim 2008; Weir et al 2012; Huang et al 2021; Liang et al 2022) and in vivo (Peters et al 2010). These particles can be functionalized to create a chemical bond with the organic matrix and improve their fracture strength.…”

Efficient Photopolymerization of Dental Resin Composites Using the Photoluminescent Long Afterglow of Sr2MgSi2O7:Eu2+,Dy3+

“…Caries is a kind of dental hard tissue damage caused by a variety of factors in the oral cavity, manifested as inorganic demineralization and decomposition of organic matter. − The continuous development of caries can cause chewing disorders and even tooth loss, which has severe influence on the living quality of patients. As a major common oral disease, caries is listed as one of the three priority diseases for prevention and treatment by the World Health Organization .…”