2000
DOI: 10.2169/internalmedicine.39.73
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Sjoegren 's Syndrome Complicated with Autoimmune Hepatitis and Antiphospholipid Antibody Syndrome.

Abstract: A 56-year-old Japanese female simultaneously developed thrombocytopenia, sicca symptoms, and an elevation of transaminase. Antiphospholipid antibodies were detected in her serum. The presence of anti-SS-A antibodies in the serum and sialectasis, disclosed by sialography, suggested the presence of primary Sjogren's syndrome (SjS). The laboratory data and the biopsy of the liver showed compatible findings with autoimmune hepatitis (AIH). Thrombocytopenia and liver dysfunction satisfactorily responded to corticos… Show more

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Cited by 19 publications
(11 citation statements)
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“…Although antiphospholipid syndrome also accompanies thrombocytopenia, this patient was negative for anti-phospholipid Abs and exhibited no signs of vascular thrombosis or any other stigmata of this syndrome (15). Association ofAIH and the presence of anti-phospholipid Abs has recently been described (16,17). However, no mention has hitherto been made of antiphospholipid Ab titers in most previous reports concerning AIH patients complicated by thrombocytopenia.…”
Section: Discussionmentioning
confidence: 73%
“…Although antiphospholipid syndrome also accompanies thrombocytopenia, this patient was negative for anti-phospholipid Abs and exhibited no signs of vascular thrombosis or any other stigmata of this syndrome (15). Association ofAIH and the presence of anti-phospholipid Abs has recently been described (16,17). However, no mention has hitherto been made of antiphospholipid Ab titers in most previous reports concerning AIH patients complicated by thrombocytopenia.…”
Section: Discussionmentioning
confidence: 73%
“…Katayama et al described a case of AIH combined with Sjögren's and antiphospholipid syndromes (20). This 56-year-old Japanese female simultaneously developed thrombocytopenia, sicca symptoms, and an elevation of transaminase.…”
Section: Discussionmentioning
confidence: 96%
“…Antiphospholipid antibodies have been detected in 3-14% of AIH patients. 7 Katayama et al 8 with prednisolone. The patient developed lung infarction, and subsequent evaluation revealed the presence of IgM anticardiolipin antibody.…”
Section: Sirmentioning
confidence: 99%