“…The longitudinal study design has been previously used to evaluate diagnostic reliability of other growth indicators, 5,18 but it has never been used to study their relationship to dental maturity. Moreover, while previous studies correlated dental maturation stages with other growth indicators such as CVM 8,14,16,[23][24][25][26][27] or HWM, 12,24,28 the present study focused, for the first time, on the mandibular growth peak itself. The present results showed that none of the maturational stages of the mandibular second molar reach satisfactory diagnostic reliability to consistently identify the mandibular growth peak, irrespective of the sample of origin.…”