Skin-associated adipocytes in skin barrier immunity: A mini-review

Guan, Jingyan; Wu, Chuanxi; He, Yunfan; Lu, Feng

doi:10.3389/fimmu.2023.1116548

Cited by 7 publications

(1 citation statement)

References 93 publications

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“…Sensor-binding 3D regenerative membranes are widely used in clinical research. Skin contributes critically to health via its role as a barrier tissue against a multitude of external pathogens [ 157 ]. Hence, the demand for skin biofabrication is still rising with great speed.…”

Section: Sensorsmentioning

confidence: 99%

Development and Prospective Applications of 3D Membranes as a Sensor for Monitoring and Inducing Tissue Regeneration

Wu,

Chen,

Zhao

et al. 2023

Membranes

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For decades, tissue regeneration has been a challenging issue in scientific modeling and human practices. Although many conventional therapies are already used to treat burns, muscle injuries, bone defects, and hair follicle injuries, there remains an urgent need for better healing effects in skin, bone, and other unique tissues. Recent advances in three-dimensional (3D) printing and real-time monitoring technologies have enabled the creation of tissue-like membranes and the provision of an appropriate microenvironment. Using tissue engineering methods incorporating 3D printing technologies and biomaterials for the extracellular matrix (ECM) containing scaffolds can be used to construct a precisely distributed artificial membrane. Moreover, advances in smart sensors have facilitated the development of tissue regeneration. Various smart sensors may monitor the recovery of the wound process in different aspects, and some may spontaneously give feedback to the wound sites by releasing biological factors. The combination of the detection of smart sensors and individualized membrane design in the healing process shows enormous potential for wound dressings. Here, we provide an overview of the advantages of 3D printing and conventional therapies in tissue engineering. We also shed light on different types of 3D printing technology, biomaterials, and sensors to describe effective methods for use in skin and other tissue regeneration, highlighting their strengths and limitations. Finally, we highlight the value of 3D bioengineered membranes in various fields, including the modeling of disease, organ-on-a-chip, and drug development.

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Section: Sensorsmentioning

confidence: 99%