Skin bacterial structure of young females in China: The relationship between skin bacterial structure and facial skin types

Zheng, Yumei; Liang, Heng; Zhou, Mingyue; Song, Liya; He, Congfen

doi:10.1111/exd.14105

Cited by 19 publications

(18 citation statements)

References 34 publications

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“… 9 The microbiota present on the skin (which consists of both commensal and pathogenic microbes) can be transient or resident, 10 , 11 and these microbes affect the skin barrier and epithelial innate immune responses. 12 , 13 When the barrier is disturbed or the balance between commensal microbiota and pathogens is disrupted, skin disease or even systemic disease may occur. 14 , 15 …”

Section: Introductionmentioning

confidence: 99%

Analysis of the Bacterial Flora of Sensitive Facial Skin Among Women in Guangzhou

Qiao¹,

Huang²,

Leng³

et al. 2021

CCID

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Background Sensitive skin (SS) is easily irritated by various environmental stimuli, and epidemiological surveys surprisingly find that self-perceived SS is widespread worldwide. Objective To investigate whether SS is linked to changes in the skin bacterial population using 16S rRNA sequencing and bioinformatic analysis. Patients and Methods According to both the Huaxi SS Questionnaire and Lactic Acid Stimulation Test, 60 female volunteers in Guangzhou were classified into normal skin (NS) and SS groups. Skin barrier parameters were assessed by the CK skin tester. The DNA of the bacterial flora on the facial skin surface was extracted and was subjected to 16S rRNA sequencing. Results The skin hydration was significantly lower in the SS group compared to the NS group ( P =0.032). Based on 16S rRNA sequencing and bioinformatic analysis, the number of operational taxonomic units (OTUs) significantly decreased in the SS group ( P =0.0235, SS vs NS). The relative abundance of Neisseriaceae in SS group decreased significantly ( P <0.05, SS vs NS), while that of Neisseria (within the Neisseriaceae family) increased significantly ( P <0.05, SS vs NS). Conclusion SS is accompanied by a decrease in species diversity and richness, which may be relevant to the weakening of the microbial barrier (due to the increase of Neisseria or the decrease of Neisseriaceae ). Thus, corresponding treatment for Neisseriaceae may be a new idea in the treatment of SS.

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Section: Introductionmentioning

confidence: 99%

Analysis of the Bacterial Flora of Sensitive Facial Skin Among Women in Guangzhou

Qiao¹,

Huang²,

Leng³

et al. 2021

CCID

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“…For example, the β -diversity of sensitive skin and different skin types did not exhibit significant differences from healthy skin. 26 , 57 , 58 Hence, we inferred that it could possibly take a remarkable change in the skin physiological status to shift the overall species composition and relative abundance of bacteria, like psoriasis or other diseases. 59 , 60 …”

Section: Discussionmentioning

confidence: 98%

“…The taxonomy of each OTU representative sequence was analyzed by RDP Classifier ( http://rdp.cme.msu.edu/ , version 2.2) against the 16S rRNA database (eg Silva v138) using confidence threshold of 0.7. 26 …”

Section: Methodsmentioning

confidence: 99%

Regular Late Bedtime Significantly Affects the Skin Physiological Characteristics and Skin Bacterial Microbiome

Shao¹,

Jiang²,

Li³

et al. 2022

CCID

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Background Late bedtime is a common form of unhealthy sleep pattern in adulthood, which influences circadian rhythm, and negatively affects health. However, little is known about the effect of regular late bedtime on skin characteristics, particularly on skin microbiome. Objective To investigate the changes and effects of the regular late bedtime on skin physiological parameters and facial bacterial microbiome of 219 cases of Chinese women aged 18–38 years living in Shanghai. Methods Based on the Self-Evaluation Questionnaire, bedtime was categorized as 11:00 PM; thus, the volunteers were divided into early bedtime group (S0) and late bedtime group (S1). The physiological parameters of facial skin were measured by non-invasive instrumental methods, and the skin microbiome was analyzed by 16S rRNA high-throughput sequencing. Results The skin physiological parameters of the late bedtime group exhibited significant decrease in skin hydration content, skin firmness (F4) and elasticity (R2), while TEWL, sebum and wrinkle significantly increased. The result indicated that late bedtime significantly impaired the integrity of skin barrier, damaged skin structure, and disrupted water–oil balance. Furthermore, the analysis of α-diversity, Sobs, Ace and Chao index were found to significantly decrease ( P < 0.05) in the late bedtime group, suggesting that late bedtime reduced both the abundance and the diversity of facial bacterial microbiota. Moreover, the abundance of Pseudomonas increased significantly, while Streptococcus , Stenotrophomonas , Acinetobacter, Haemophilus, Actinomyces and Neisseria decreased significantly. In addition, Spearman correlation analysis revealed strong correlations between the microbiota and the physiological parameters. Notably, the abundance of Pseudomonas significantly positively correlated with skin firmness and elasticity, but significantly negatively correlated with skin hemoglobin content, melanin content and skin hydration. Conclusion Bedtime is an important factor in maintaining skin health. Regular late bedtime not only damages the skin barrier and skin structure but also reduces the diversity and composition of facial bacterial microbiome.

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“…In south China, the temperature and humidity of the Hakka area keep increasing during these seasons, and microbes become more and more active, which causes more infections, including human skin diseases, respiratory disease, rheumatism syndrome, etc. [ 75 – 77 ]. Therefore, most Hakka herbs were employed for infectious diseases, which suggests their potential as anti-infectious agents.…”

Section: Discussionmentioning

confidence: 99%

Ethnobotanical study of Hakka traditional medicine in Ganzhou, China and their antibacterial, antifungal, and cytotoxic assessments

Yang

Aissa

et al. 2022

BMC Complement Med Ther

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Background Traditional herbs played a crucial role in the health care of the Hakka people. However, studies to identify these traditional herbs are few. Here we document and assess the potential of these plants for treating microbial infections. Many herbs used by the Hakka people could potentially be a novel medicinal resource. Methods Local herb markets were surveyed via semi-structured interviews, complemented by direct observations to obtain information on herbal usage. For each herb selected for this study, extracts in four different solvents were prepared, and tested for activity against 20 microorganisms, as well as cancerous and noncancerous cells. All data were subjected to cluster analysis to discover relationships among herbs, plant types, administration forms, solvents, microorganisms, cells, etc., with the aim to discern promising herbs for medicine. Results Ninety-seven Hakka herbs in Ganzhou were documented from 93 plants in 62 families; most are used for bathing (97%), or as food, such as tea (32%), soup (12%), etc. Compared with the Chinese Pharmacopoeia and Chinese Materia Medica, 24 Hakka medicines use different plant parts, and 5 plants are recorded here for the first time as traditional medicines. The plant parts used were closely related with the life cycle: annual and perennial herbs were normally used as a whole plant, and woody plants as (tender) stem and leaf, indicating a trend to use the parts that are easily collected. Encouragingly, 311 extracts (94%) were active against one or more microorganisms. Most herbs were active against Gram-positive bacteria, such as Staphylococcus aureus (67%), Listeria innocua (64%), etc. Cytotoxicity was often observed against a tumor cell, but rarely against normal cells. Considering both antimicrobial activity and cytotoxicity, many herbs reported in this study show promise as medicine. Conclusion Hakka people commonly use easily-collected plant parts (aerial parts or entire herb) as medicine. External use of decoctions dominated, and may help combating microbial infections. The results offer promising perspectives for further research since little phytopharmacology and phytochemistry has been published to date. Graphical Abstract

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Skin bacterial structure of young females in China: The relationship between skin bacterial structure and facial skin types

Cited by 19 publications

References 34 publications

Analysis of the Bacterial Flora of Sensitive Facial Skin Among Women in Guangzhou

Analysis of the Bacterial Flora of Sensitive Facial Skin Among Women in Guangzhou

Regular Late Bedtime Significantly Affects the Skin Physiological Characteristics and Skin Bacterial Microbiome

Ethnobotanical study of Hakka traditional medicine in Ganzhou, China and their antibacterial, antifungal, and cytotoxic assessments

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